Application of TCM and Western Medical Therapeutic Evaluation Method ologies for the Combination Treatment with Feiliuping Extract and Chemotherapy in Advanced Nonsmall-Cell Lung Cancer
ZHANG Peitong, LIN Hongsheng, YU Mingwei, et al. Application of TCM and Western Medical Therapeutic Evaluation Method ologies for the Combination Treatment with Feiliuping Extract and Chemotherapy in Advanced Nonsmall-Cell Lung Cancer[J]. Journal of Traditional Chinese Medicine2012, 53(5): 403-406.
ZHANG Peitong, LIN Hongsheng, YU Mingwei, et al. Application of TCM and Western Medical Therapeutic Evaluation Method ologies for the Combination Treatment with Feiliuping Extract and Chemotherapy in Advanced Nonsmall-Cell Lung Cancer[J]. Journal of Traditional Chinese Medicine2012, 53(5): 403-406.DOI: 10.13288/j.11-2166/r.2012.05.030.
Objective To compare the characteristic and differenc e between TCM and Western Medical therapeutic evaluation methodologies for the combination treatme nt with Feiliuping Extract(extract for treating lung cancer) and chemotherapy i n advanced nonsmall-cell cancer(NSCLC).Methods Using prospective random-control method
totally 119 patients with advan ced NSCLC were divided into the chemotherapy group and combined therapy group.Chemotherapy was administrated to 56 patients in the chemotherapy group
and F eiliuping Extract was added to 63 patients in the combined group.The course of treatment lasted for 42 days.The curative effect was observed by evaluating the symptoms
tumor body
Karnofsky score
weight and immune function.Results Acco rding to Standard for Therapeutic Effect Evaluation of Solid Tumor by WHO
the t herapeutic effect was no significantly different between groups(P>0.05).A ccord ing to Standard for Therapeutic Effect Evaluation of TCM treatment for Advanced Lung Cancer
the therapeutic effect of the combined group was superior to that o f the chemotherapy group(P<0.05).Comparing with the chemotherapy group
F eiliu ping Extract could relieve symptoms especially pulmonary symptoms
promote the i mmune function
increase the count of WBC and granulocyte and improve constipati on condition efficiently(P<0.05 or P<0.01).There was no significant difference between groups in Karnofsky score
weight
middle life span and survival rate o f one year(P>0.05).Conclusion Comparing with Sta ndard for Therapeutic Effect E valuation of Solid Tumor by WHO
Standard for Therapeutic Effect Evaluation of T CM treatment for Advanced Lung Cancer could better reflect the characteristics a nd advantages of TCM treatment for tumor.Feiliuping Extract is effective for ad vanced NSCLC by supplementing qi
nourishing yin
activating blood and eliminati ng toxin with its synergy and attenuation.