Objective To evaluate the clinical effect of Wuling Powder（powder of five Poria）and Wuling Decoction（decoction of five Poria）for nephritic syndrome patients of water-damp collecting internally syndrome.Methods Forty-seven nephritic syndrome patients of water-damp collecting internally syndrome were randomized into Wuling Powder group and Wuling Decoction group.Six ca- ses were eliminated or shed off.The valid cases were 41

with 21and 20in the Wuling Powder group and Wuling Decoction group re- spectively.Wuling Powder group was given Wuling Powder

9g once

three times a day.Wuling Decoction group was given Wuling Decoction

one dose daily

taken twice.The treatment lasted for 4weeks.The urinary output

the average body weight

24-hour uri- nary protein quantity（24hUPQ）and plasma albumin（ALB）was observed.Results After treatment

the average urinary output was significantly increased while the body weight was decreased in both groups（P<0.05）.The difference between groups in the average u- rinary output and body weight was statistically significant（P<0.05）.There was no significant difference in 24hUPQ and ALB be- tween groups（P>0.05）.Conclusion Wuling Powder is better at disinhibiting water and dispersing swelling than Wuling Decoction for nephritic syndrome patients of water-damp collecting internally syndrome.