LIU Jianing. Clinical Research on Shenling Baizhu Powder for Leucopenia after Chemotherapy[J]. Journal of Traditional Chinese Medicine2012, 53(12): 1038-1041.
LIU Jianing. Clinical Research on Shenling Baizhu Powder for Leucopenia after Chemotherapy[J]. Journal of Traditional Chinese Medicine2012, 53(12): 1038-1041.DOI: 10.13288/j.11-2166/r.2012.12.005.
Objective To observe the therapeutic effect of Shenling Baizhu Powder(Ginseng
Poria
and White Atractylodes Powder) on leucopenia after chemotherapy and improvement of quality of life(QOL).Methods Eighty four leucopenia patients after chemotherapy of gynecologic malignancies were randomized into treatment group and control group
with 42 in each.The control group was given leucogen and batilol and the treatment group was given Shenling Baizhu Powder in addition.One treatment course lasted for 4 weeks.The therapeutic effect was evaluated after two treatment courses.White blood cell(WBC)
red blood cell(RBC)
hemoglobin(HGB)
platelet(PLT)
lymphocytes(LYM)
granulocytes(GRAN)
PLT%
LYM%
monocytes(MON)%
GRAN%
Spitzer scores and San Francisco Comprehensive Approaches to Raising Educational Standards(CARES-SF) scores were observed.Results After treatment
WBC
RBC
HGB
PLT
LYM
GRAN
PLT%
LYM%
MON% and GRAN% were significantly improved in both groups(P<0.05).Comparing with the control group
WBC
HGB
LYM
MON% and GRAN% were improved significantly in the treatment group(P<0.05).The total effective rate of the treatment group and the control group was 90.48% and 73.81% respectively
with a significant difference between groups(P<0.05).The main symptoms and signs were relieved and the Spitzer scores and CARES-SF scores were improved significantly in both groups after treatment(P<0.05).Comparing with the control group
the Spitzer scores and CARES-SF scores were significantly improved in the treatment group after treatment(P<0.05).Conclusion Shenling Baizhu Powder is effective for leucopenia after chemotherapy of gynecologic malignancies and could significantly improve QOL of the patients.