Objective To observe the therapeutic effect of Zishen Shengjing Decoction（decoction to enrich the kidney and engender essence） for oligospermia and asthenospermia.Methods Totally 206 cases of oligospermia and asthenospermia with kidney deficiency syndrome were given modified Zishen Shengjing Decoction

one dosage daily

for 3 months.The sperm count and motility was observed before the treatment and after 1.5 months and 3 months of the treatment.Results There were 186 cases of asthenospermia with 124 cases of simple asthenospermia and 62 cases of oligospermia and asthenospermia.After 1.5 and 3 months of the treatment

there were 17 cases（9.1%） and 90 cases（48.4%） of sperm motility A≥25% or（and） A+B≥50% respectively.The sperm motility improved significantly after 1.5 and 3 months of the treatment（P<0.01）

especially after 3 months of the treatment（P<0.01）.There were 82 cases of oligospermia with 20 cases of simple oligospermia and 62 cases of oligospermia and asthenospermia.After 1.5 and 3 months of the treatment

there were 10 cases（12.2%） and 42 cases（51.2%） of sperm density≥20×106/ml respectively.The sperm density improved significantly after 1.5 and 3 months of the treatment（P<0.01）

especially after 3 months of the treatment（P<0.01）.Conclusion Zishen Shengjing Decoction is effective for oligospermia and asthenospermia.It could obviously improve sperm density and motility.