1. 河南省中医院妇科
2. 河南省人民医院
纸质出版:2012
移动端阅览
[1]李艳青,陈顺强,孙红.清宫胶囊治疗药物流产后出血患者49例临床观察[J].中医杂志,2012,53(16):1387-1389+1393.
LI Yanqing1, CHEN Shunqiang2, SUN Hong1. Clinical Observation on Qinggong Capsule for 49 Cases of Hemorrhage after Drug-induced Abortion[J]. Journal of Traditional Chinese Medicine2012, 53(16): 1387-1389.
[1]李艳青,陈顺强,孙红.清宫胶囊治疗药物流产后出血患者49例临床观察[J].中医杂志,2012,53(16):1387-1389+1393. DOI: 10.13288/j.11-2166/r.2012.16.001.
LI Yanqing1, CHEN Shunqiang2, SUN Hong1. Clinical Observation on Qinggong Capsule for 49 Cases of Hemorrhage after Drug-induced Abortion[J]. Journal of Traditional Chinese Medicine2012, 53(16): 1387-1389. DOI: 10.13288/j.11-2166/r.2012.16.001.
目的观察中药清宫胶囊治疗药物流产后出血的临床疗效。方法将97例药物流产后出血患者随机分为治疗组49例和对照组48例。两组均采用口服药物流产
服药后第7天治疗组口服清宫胶囊
每次4粒
每日3次;对照组口服益母草胶囊
每次4粒
每日3次。5天为1个疗程
用药不超过3个疗程。两组分别于就诊当天(治疗前)、治疗后第5、10、18天检测血人绒毛膜促性腺激素β亚基(β-HCG)、雌二醇(E2)、孕酮(P)水平
并观察药物流产后出血时间及转经情况。结果治疗组49例中治愈25例(51.02%)
有效22例(44.90%)
无效2例(4.08%);对照组48例中治愈18例(37.50%)
有效19例(39.58%)
无效11例(22.92%)
两组比较差异有统计学意义(P<0.05)。治疗组药物流产后平均出血时间短于对照组(P<0.01)。治疗组在9天内出血停止的例数明显多于对照组(P<0.01)。治疗组转经周期、转经经期均短于对照组(P<0.05或P<0.01)。两组治疗后5、10、18天β-HCG、E2、P水平与治疗前比较差异均有统计学意义(P<0.05或P<0.01)。治疗后5、10、18天两组间β-HCG比较差异有统计学意义(P<0.05)。结论清宫胶囊可有效缩短药物流产患者出血时间及月经恢复时间
减少出血量
其作用与加强子宫收缩
减少体内β-HCG分泌
促进子宫内膜修复有关。
Objective To observe the therapeutic effect of Qinggo ng Capsule(capsule to repair uterine) on hemorrhage after drug-induced abortion.Methods Nighty seven patients with hemorrhage after drug-induced abortion were randomized into treatment group of 49 cases and control group of 48 cases.Both groups were given mifepristone and misoprostol to induce abortion
in addition
the treatment group and control group was given Qinggong Capsule and Leonurus Capsule respectively on the 7th day
4 capsules once
t hree times daily.One treatment course lasted for 5 days.The medicat ion was not more than three courses in both groups.Beta-human chorionic gonado tropin(β-HCG)
estradiol(E2)
progesterone(P) were observed on the 1st
5th
10th
18th day
and bleeding time and menstrual recovery were observed after treatment.Results Of 49 cases in the treatment group
there were 25 cases(51.02%) cured
22 cases(44.90%) effective
and 2 cases(4.08%) ineffective.And of the 48 cases in the control group
there were 18 cases(37.50%) cured
19 cases(39.58%) effective
and 11 ca ses(22.92%) ineffective.The difference between groups was sta tistically significant(P<0.05).The average bleeding time was(10.38±0. 36) and (13.54±0.56) days in the treatment group and control group respectively
with significant difference between groups(P<0.01).The cases of bleeding sto pped within 9 days in the treatment group were much more than those in the control gr oup(P<0.01).The period of menstrual recovery was(30.5±5.2) and(33.8± 8.6) days and the menstrual duratio n was(6.1±3.5) and(9.9±5.1) days in the treatment group and control group re spectively.The time of menstrual recovery and menstrual duration in the treat ment group were shorter than those in the control group(P<0.05 or P<0.0 1).On the 5th
10th and 18th day of treatment
there were significant differences in βHCG
E2 and P in both groups as compared with those before treatment(P<0.05 or P<0.01).On the 5th
10th and 18th day of treatment
there was significant difference b etween groups in β-HCG(P<0.05).Conclusion Qinggong Capsule could obviously reduce the bleeding time and bleeding amount and shorten the time of men strual recovery
which maybe relevant to strengthening the contraction of the ut erus
reducing the secretion of β-HCG and promoting the repair of the endometr ium.
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