Objective To evaluate the therapeutic effect and safe ty of quickening blood and transforming stasis on recurrent spontaneous abortion from literature study.Methods Clinical research literature on quickeni ng blood and transforming stasis for recurrent spontaneous abortion was searched from China National Know ledge Internet（CNKI）

VIP database

Chinese Biomedical Literature Database（CBM） and Wanfang Database.Systematic review was used to extract the syndrome ident ification

treatment

therapeutic effect and adverse event from the literature. The therapeutic effect

safety and feasibility of quickening blood and transform ing stasis for recurrent spontaneous abortion were analyzed.Res ults Twenty five articles were included.Thirteen articles reported the patients with blood stas is syndrome or root deficiency and tip repletion syndrome with blood stasis.The commonly used Chinese medicinals to quicken blood and transform stasis were Dan ggui（Radix Angelicae Sinensis）

Danshen（Radix et Rhizoma Salviae Miltiorrhizae）

Chishao（Radix Paeoniae Rubra）

Chuanxiong（Rhizoma Chuanxiong）

Yimucao（Her ba Leonuri）

Honghua（Flos Carthami）

Puhuang（Pollen Typhae）

Taoren（Semen Per sicae） and Wulingzhi（Faeces Togopteri）.Comparing with conventional western med icine and Chinese medicine

the combination of quickening blood and transforming stasis medicinals could improve the live birth rate of patients with recurrent spontaneous abortion.There was no obvious adverse event reported.Conclusion Qu ickening blood and transforming stasis is valuable and feasible for recurrent sp ontaneous abortion.Since the quality of current studies is generally low

it is necessary to conduct randomized-controlled trials to confirm the therapeutic e ffect and safety of quickening blood and transforming stasis.