Objective To observe the relationship between renal h emodynamics and Chinese medicine syndrome type in diabetic nephropathy（DN）.Methods Totally 489 cases of DN and 50 cases of normal subjects were selected.Color Doppler was used to observe the renal perfusion grade.Pulsed wave Doppler was used t o observe spectrum of interlobar arterial blood flow.The values of peak systolic velocity（VS）

diastolic velocity（VD）

average maximum velocity（VM）

pulsatile index（PI） and resistance index（RI） were measured.Results As disease progressed

the syndrome developed in the order of yin deficiency dryness-heat syndrome

qi-yin deficiency syndrome

yin-yang de ficiency syndrome and yang deficiency stasis obstruction syndrome.The renal art ery blood flow reduced gradually

with significant differences between groups（ P <0.01）.The values of VS

VD and VM decreased gradually

especially in qi-yin de ficiency group

yin-yang deficiency group and yang deficiency stasis obstructio n group as compared with the normal control group and yin deficiency dryness-hea t group（P<0.01）.There were significant differences among other three groups（P <0.05 or P<0.01）.The values of PI and RI gradually increased

especially in qi-yin deficiency group

yin-yang deficiency group and yang deficiency stasis ob struction group as compared with the normal control group（P<0.01）.Conclusion Renal hemodynamics is related to Chinese medicine syndrome type in DN and it could be used as an objective indicator for syndrome diagnosis.