CHEN Weiwen1, ZHOU Dongmei1, WANG Ping1, et al. A Multi-Center Clinical Validation Study of Chinese Medicine Treatment Program for Psoriasis Vulgaris[J]. Journal of Traditional Chinese Medicine2012, 53(18): 1557-1561.
CHEN Weiwen1, ZHOU Dongmei1, WANG Ping1, et al. A Multi-Center Clinical Validation Study of Chinese Medicine Treatment Program for Psoriasis Vulgaris[J]. Journal of Traditional Chinese Medicine2012, 53(18): 1557-1561.DOI: 10.13288/j.11-2166/r.2012.18.009.
Objective To validate the Chinese medicine treatment program for psoria sis vulgaris
determine its therapeutic effect and lay foundation for further op timization.Methods Totally 186 psoriasis vulgaris pati ents were included
of which 131 cases were blood heat syndrome
34 were blood d ryness syndrome
and 21 were blood stasis syndrome.According to syndrome type
they were treated with the method of cooling blood and removing toxin
nourishin g blood and removing toxin and activating blood and removing toxin respectively.External treatment including moist compress
medicated bath
acupuncture were a lso used.Lesion area
psoriasis area and severity index(PASI) and side effect were observed on the 8th and 12th week.Results Oral ad ministration of deco ction was the most widely used Chinese medication
followed by ointment
medicat ed bath
oral administration of proprietary Chinese medicine and moist compress.There were 158 patients finished the eight-week treatment and the total effect i ve rate was 79.7%
among which the effective rate of blood heat syndrome
blood dryness syndrome and blood stasis syndrome was 78.2%
82.4% and 82.6% respective ly
with no significant difference between different syndromes(P>0.05).Th ere w ere 100 patients finished the twelve-week treatment and the total effective rat e was 89.0%
among which the effective rate of blood heat syndrome
blood dryness syndrome and blood stasis syndrome was 92.1%
89.5% and 77.8%
with no signific ant difference between different syndromes(P>0.05).Conclu sion Blood heat syndr ome is the most common syndrome in psoriasis vulgaris.Oral administration of de coction
ointment
medicated bath
oral administration of proprietary Chinese me dicine and moist compress are widely used Chinese medication for psoriasis vulga ris.Chinese medication for psoriasis is effective with good compliance.