Objective To observe the therapeutic effect of qi-b o osting blood-quickening therapy combined with continuous blood purification（CB P） for critically il l patients.Methods Forty critically-ill patients with qi-deficiency blood-stasis syndrome were randomized into control group of 17 c ases and treatment group of 23 cases.The control group was treated with continu ous venovenous hemodiaf iltration（CVVH） and the treatment group was added with qi-boosting blood-quic kening therapy.The scores of Chinese medical s yndromes

acute physiology and chronic health evaluation Ⅱ（APACHE-Ⅱ）

coagulation indicators

heparin total

mean blood pressure（MBP）

blood gas anal ysis indexes

renal function

levels of cytokines and efficacy of Chinese medica l syndromes were observed.Results The heparin total in the control group decreased sig nificantly after treatmen t（P<0.05）.The platelet（PLT）

heparin total and MBP in t he treatment group decreased significantly after treatment（P<0.05）

with s ign ificant difference in PLT and heparin total between groups（P<0.05）.The sc ores of APACHE Ⅱ and Chinese medical syndromes decreased significantly in both group s after treatment

especially in scores of Chinese medical syndromes in the trea tment group（P<0.05）.The blood gas analysis indexes decreased si gnificantly in both groups after treatment（P<0.05）.Blood urea nitrogen（B UN）

serum creatinine（Scr）

tumor necrosis factor-α（TNF-α） and interleukin-6（IL-6） decreased significantly in both groups after treatment（P<0.05）

with no significant difference betwe en g roups（P>0.05）.The total effective rate of the treatment group（65.2%） wa s superior to that of the control group（52.9%

P<0.05）.Conclusion Qi-boosting blood-quickening therapy combined with CBP is effective for critic ally ill patients with qi-deficiency blood-stasis syndrome

which is superior to simple CBP in improving scores of Chin ese medical syndromes and reducing the dosage of heparin.