QI Xuelin, YANG Yafeng, HUANG Xiaohong. Clinical Observation on Yiguan Brew Combined with Western Medication f or 40 Cases of Diabetic Gastroparesis with Stomach Yin Deficiency Syndrome[J]. Journal of Traditional Chinese Medicine2012, 53(18): 1566-1569.
QI Xuelin, YANG Yafeng, HUANG Xiaohong. Clinical Observation on Yiguan Brew Combined with Western Medication f or 40 Cases of Diabetic Gastroparesis with Stomach Yin Deficiency Syndrome[J]. Journal of Traditional Chinese Medicine2012, 53(18): 1566-1569.DOI: 10.13288/j.11-2166/r.2012.18.028.
Objective To observe the effect of Yiguan Brew(Al l-the-Way-Through Brew) combined with western medication on diabetic gastropa resis with stomach y in deficiency syndrome.Methods Eighty diabetic gastrop are sis patients with stomach yin deficiency syndrome were randomized into treat ment group and control group
with 40 in each.Both groups were given repaglinid e and metformin hydrochloride tablets to control blood sugar.The treatment grou p was added with Yiguan Brew
one dose daily.The control group was added with M osapride dispersible tablets
10mg per time
3 times daily.One treatment course lasted for 2 weeks.Scores of clinical symptoms
gastric half emptying time(GE T1/2) and lag phase time(Tlag) were observed before and after treatment.Results After treatment
GET1/2 and Tlag improved significantly in both groups(P<0.05 or P<0.01)
especially in the treatment group(P<0.01).The total effective rate of the treatment group and the control group was 75.00% and 62.5 0% respectively.The treatment group was superior(P<0.05).After treatment
there were significant differences in early satiety
epigastric fullness
loss of appetite
heartburn
nausea
vom iting and total symptom score in the treatment group as compared with before tre atment(P<0.01).After treatment
there were significant differences in ear ly satiety
epiga stric fullness and total symptom score in the control group as compared with bef ore treatment(P<0.05).After treatment
there were significant differences in epigastric full ness
heartburn
nausea
vomiting and loss of appetite between groups(P<0.01).Two weeks after treatment
early satiety
epigastric fullness
loss of appe tite
tongue
pulse and total symptom score in the treatment group were significantly lower than those in the control group(P<0.05 or P<0.01).C onclusion Modified Yiguan Brew could obviously relieve symptoms and pro mote gastric emptying for diabetic gasroparesis with stomach yin deficiency synd rome.