1. 南通市良春中医药研究所
2. 南通市中医院
3. 南京市中医院
4. 常州市中医医院
5. 南通市第四人民医院
6. 苏州市中医医院
7. 江苏省中西医结合医院
8. 苏州大学附属第一医院
纸质出版:2012
移动端阅览
[1]朱婉华,张爱红,顾冬梅,蒋熙,徐蕾,周正球,陈普建,高忠恩,王小超,陈志伟.痛风性关节炎中医证候分布规律探讨[J].中医杂志,2012,53(19):1667-1670.
ZHU Wanghua1, ZHANG Aihong1, GU Dongmei1, et al. Exploration of the Distribution Regularity of TCM Syndrome in Gouty Arthritis[J]. Journal of Traditional Chinese Medicine2012, 53(19): 1667-1670.
[1]朱婉华,张爱红,顾冬梅,蒋熙,徐蕾,周正球,陈普建,高忠恩,王小超,陈志伟.痛风性关节炎中医证候分布规律探讨[J].中医杂志,2012,53(19):1667-1670. DOI: 10.13288/j.11-2166/r.2012.19.013.
ZHU Wanghua1, ZHANG Aihong1, GU Dongmei1, et al. Exploration of the Distribution Regularity of TCM Syndrome in Gouty Arthritis[J]. Journal of Traditional Chinese Medicine2012, 53(19): 1667-1670. DOI: 10.13288/j.11-2166/r.2012.19.013.
目的探讨痛风性关节炎患者中医证候的分布规律。方法收集江苏省8家医院444例痛风性关节炎患者临床资料
辨证分为湿热蕴结证、瘀热阻滞证、痰浊阻滞证、肝肾阴虚证。统计患者病程、年龄、地区
并检测尿酸、血沉、C反应蛋白等实验室指标
总结各证候患者病程、年龄、地域、分期、实验室指标等方面的分布规律。结果 444例痛风性关节炎患者中湿热蕴结证150例
占33.78%;瘀热阻滞证131例
占29.50%;痰浊阻滞证117例
占26.35%;肝肾阴虚证46例
占10.36%。瘀热阻滞证和肝肾阴虚证病程长于湿热蕴结证和痰浊阻滞证(P<0.05);年龄较轻者主要表现为湿热蕴结证
较长者主要表现为瘀热阻滞证(P<0.05);急性期以湿热蕴结证为主
间歇期以痰浊阻滞证为主
慢性期以瘀热阻滞证为主(P<0.05);各地域间及血尿酸、血沉、C反应蛋白方面证候构成差异均有统计学意义(P<0.05)。结论痛风性关节炎患者中医证候分布情况与患者病程、年龄、地域、分期、炎性指标等因素具有相关性。
ObjectiveTo explore the distribution regularity of TCM syndrome in gouty arthritis.MethodsTotally 444 cases of gouty arthritis were collected from 8 hospitals in Jiangsu province and divided into four TCM syndromes
i.e.damp-heat brewing and binding syndrome
stasis heat obstruction syndrome
phlegm turbidity obstruction syndrome and liver-kidney yin deficiency syndrome.The disease duration
age and region was counted and blood uric acid(BUA)
erythrocyte sedimentation rate(ESR) and C-reactive protein(CRP) were detected.The distribution regularity of TCM syndromes were analyzed according to different disease duration
age
region
stage and laboratory parameters.ResultsThere were 150 cases(33.78%) of damp-heat brewing and binding syndrome
131 cases(29.50%) of stasis heat obstruction syndrome
117 cases(26.35%) of phlegm turbidity obstruction syndrome and 46 cases(10.36%) of liver-kidney yin deficiency syndrome in 444 cases of gouty arthritis.The disease duration of stasis heat obstruction syndrome and liver-kidney yin deficiency syndrome was longer than that of the damp-heat brewing and binding syndrome and phlegm turbidity obstruction syndrome(P<0.05).The younger was mainly with damp-heat brewing and binding syndrome and the elder was mainly with stasis heat obstruction syndrome(P<0.05).The main syndrome was damp-heat brewing and binding syndrome
phlegm turbidity obstruction syndrome and stasis heat obstruction syndrome in the acute period
intermittent period and chronic period respectively(P<0.05).There were significant differences between syndromes in BUA
ESR and CRP as well(P<0.05).ConclusionThe distribution of TCM syndrome in gouty arthritis is related to the disease duration
age
region
stage and inflammatory markers of the patients.
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