Objective To observe the therapeutic effect of electro-acupuncture（EA）combined with Tiangui Capsule(Capsule for kidney-nourishing on polycystic ovary syndrome（PCOS）with obesity.Methods Sixty-seven cases of PCOS were randomized into EA combined with Chinese medication（EACM）group of 33cases and EA group of 34cases.EA on Tianshu（ST25）

Zhongwan（CV12）

Qihai（CV6）

Sanyinjiao（SP6）

Geshu（BL17）and Ciliao（BL32） was applied 3times weekly in EA group.EACM group was given Tiangui Capsule orally

twice daily for three months in addition.The treatment lasted for 3months totally.The therapeutic effect

3-month recurrence rate

follicle stimulating hormone（FSH）

lute tropic hormone（LH）

testosterone（T）

fasting plasma glucose（FPG）

fasting insulin（FINS）and insulin sensitivity index（ISI）before and after treatment were observed.Results The total effective rate of EACM group was 93.9%

which was superior to 67.6%of EA group（P<0.05）.LH

LH/FSH and T value was significantly decreased in both groups

especially in EACM group（P< 0.01）.EACM group had a better effect in decreasing FINS and ISI than EA group（P<0.01）.The follow-up was conducted after 3months of treatment and the recurrence rate of EACM group was significantly lower than that of EA group（P<0.05）.Conclusion The combo therapy of acupuncture and Chinese medication is effective for PCOS with obesity

which maybe related with decrease the level of sex hormones and insulin.