Objective To observe the dose of Gegen Qinlian Decoction [Pueraria

Scutellaria

and Coptis Decoction

decoction of Gegen（Radix Puerariae Lobatae）

Huangqin（Radix Scutellariae） and Huanglian（Rhizoma Coptidis）] for diarrhea in current clinical practice.Methods The related literatures on Gegen Qinlian Decoction for diarrhea were searched in China National Knowledge Infrastructure（CNKI） from 1995 to 2011.The literatures with clear research method

dosage and efficacy evaluation were summarized.The clinical dose

treatment characteristics and efficacy were described.Results Sixteen articles were included and infectious diarrhea

acute gastroenteritis and chronic diarrhea in adults and pediatric diarrhea were involved.The adult dose range was:9-30 g Gegen

6-15 g Huangqin

3-10 g Huanglian and 3-6 g Zhigancao（Radix et Rhizoma Glycyrrhizae Praeparata cum Melle）.The pediatric dose range was:3-15 g Gegen

2-10 g Huangqin

3-10 g Huanglian and 3-9 g Zhigancao.Conclusion Literature research shows the effective and safe dose of Gegen Qinlian Decoction for diarrhea in clinic.The dose range can provide a basis for further study on clinical dose-effect relationship of Chinese medicine.