Objective To observe the effect of Compound Danshen Dripping Pill （C DDP） combined with clopidogrel for un-stable angina （U A）.Methods Totally 102UA patients were randomized into the CDDP group （3 3cases）

clopidogrel group （3 5cases） and CDDP+clopidogrel group （3 4cases）.The patients in the CDDP group were orally taken 270mg CDDP twice daily on the basis of routine treatment.The patients in the clopidogrel group were orally taken 75mg clopidogrel once daily.The CDDP+clopidogrel group was given the combo therapy of the CDDP group and clopidogrel group.After the treatments were given to each of groups for 3weeks

the improvement of clinical symptoms and electrocardiogram （E CG） ST segment changes were evaluated.The platelet aggregation function and thromboxane B 2 （T XB 2） levels were measured before and after treatment.Results There was no significant difference between groups in the total effective rate and ECG effective rate （P> 0.05）.The platelet aggregation rates and TXB 2 levels were significantly decreased in all groups after treatment （P<0.01）

es-pecially in the CDDP+clopidogrel group （P<0.05）.Conclusion The combo therapy of clopidogrel and CDDP is more effec-tive in inhibiting platelet aggregation than single treatment.It provides the basis for clinical integrative antithrombotic therapy.