Objective To observe the clinical efficacy and safety of Wind-Coursing Lung-Diffusing and Phlegm-Transforming Throat-Disinhibiting Formula for upper airway cough syndrome（UACS）.Methods Totally 294cases of UACS were randomized into the treatment group of 196cases and control group of 98cases in each.The treatment group was given Wind-Coursing Lung-Diffusing and Phlegm-Transforming Throat-Disinhibiting Formula.The control group was given placebo.Both groups were given one dose daily for 4weeks.The disappearance rate of cough

total curative effect of cough

efficacy of Chinese medicine syndrome

cough living scale and safety was observed.Results There were 195cases in the treatment group and 96cases in the control group completed the treatment.The disappearance rate of cough

total curative effect of cough and efficacy of Chinese medicine syndrome was 59.49%

82.56%and 83.08%in the treatment group

while 19.79%

58.33%and 46.88% in the control group

with significant differences between groups（P<0.01）.The scores of cough living scale were significantly improved in the treatment group

with a significant difference between groups（P<0.05）.There was no side effect in both groups.Conclusion The Wind-Coursing Lung-Diffusing and Phlegm-Transforming Throat-Disinhibiting Formula is effective for UACS

which can obviously improve the quality of life with no side effect.