Objective To explore the genetic characteristics of blood stasis pattern of coronary heart disease（CHD）.Methods A case-controlled genealogical investigation of genetic epidemiology was used to calculate and analyze the genetic parameters such as separation ratio

heritability

genetic patterns and polygenic inheritance way of 1565CHD patients with blood stasis pattern in the observation group and 1553CHD patients without blood stasis pattern in the control group.Results The prevalence of CHD with blood stasis pattern of the relatives in the observation group was 5.24%

which was significantly higher than 1.29% in the control group（P<0.05）.The segregation ratio of the first-degree relatives in the observation group was 0.1296

which was in line with the characteristics of polygenic disease.The heritability of the first-degree and second-degree relatives in the observation group was 58.04% and 54.80% respectively

with a moderate hereditary.The theoretical incidence of the first-degree and second-degree relatives in the observation group was 8.00% and 6.20% respectively

which was close to 5.89% and 4.13% of the actual incidence.Conclusion The blood stasis pattern of CHD has a certain tendency to familial aggregation and its distribution in pedigree meets the polygenic genetic characteristics.