基于关联规则的清宫胸痹医案用药规律研究

张京春; 陈可冀; 刘玥

doi:10.13288/j.11-2166/r.2013.09.015

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基于关联规则的清宫胸痹医案用药规律研究

文献研究 | 更新时间：2021-11-17

- 基于关联规则的清宫胸痹医案用药规律研究
- Medication Laws for Chest Impediment in the Medical Records of the Qing Court Based on Association Rules
- 中医杂志 2013年54卷第9期页码：789-791
- 作者机构：
  
  中国中医科学院西苑医院
- 作者简介：
- 基金信息：
  
  首都医学科技发展基金资助项目（SF-2007-3-35）;中国博士后基金资助项目（20080430539）;中国中医科学院“名医名家传承”项目（CM20121018）;北京市中医管理局薪火传承资助项目
- DOI：10.13288/j.11-2166/r.2013.09.015
  中图分类号： R256.22
- 纸质出版：2013
- 稿件说明：
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[1]张京春,陈可冀,刘玥.基于关联规则的清宫胸痹医案用药规律研究[J].中医杂志,2013,54(09):789-791.

ZHANG Jingchun, CHEN Keji, LIU Yue. Medication Laws for Chest Impediment in the Medical Records of the Qing Court Based on Association Rules[J]. Journal of Traditional Chinese Medicine2013, 54(9): 789-791.
[1]张京春,陈可冀,刘玥.基于关联规则的清宫胸痹医案用药规律研究[J].中医杂志,2013,54(09):789-791. DOI： 10.13288/j.11-2166/r.2013.09.015.

ZHANG Jingchun, CHEN Keji, LIU Yue. Medication Laws for Chest Impediment in the Medical Records of the Qing Court Based on Association Rules[J]. Journal of Traditional Chinese Medicine2013, 54(9): 789-791. DOI： 10.13288/j.11-2166/r.2013.09.015.

摘要

目的分析清宫胸痹医案的用药及组方规律

为临床诊治胸痹疾病提供参考。方法采集《清宫医案集成》中具有完整症、证、法、方药的典型胸痹医案

建立清宫胸痹医案数据库

运用频数统计和关联规则分析清宫胸痹医案的常用药物、药对及组方规律。结果共纳入医案81则。清宫胸痹医案最常用的5味药为青皮、枳壳、瓜蒌、香附、厚朴;最常用的5个药对为大黄-枳壳、龙胆草-青皮、沉香-青皮、当归-香附、赤芍-香附;最常用的5个3位药团为当归+枳壳+香附、龙胆草+栀子+青皮、半夏+青皮+瓜蒌、沉香+延胡索+青皮、半夏+瓜蒌+黄连;最常用的5个组方结构依次为理气药+芳香化湿药+清化热痰药、理气药+芳香化湿药+清热燥湿药、理气药+清化热痰药+清热燥湿药、理气药+芳香化湿药+温化寒痰药、理气药+清化热痰药+温化寒痰药。结论清宫胸痹医案的用药以理气为主

配伍清热、化痰以及活血法。

Abstract

Objective To analyze the laws of medication and formula composition for chest impediment in the medical records of the Qing Court（MRQC）and provide a reference for clinical practice.Methods The typical medical cases with complete symptoms

patterns

therapies

formulas and medicinals in Integrated MRQC（IMRQC

清宫医案集成）were collected and the database of MRQC for chest impediment was established.The commonly used medicinals

drug pairs and formula composition laws were analyzed with frequency statistics and association rules.Results Eighty one medical cases were included.The top 5 frequently-used medicinals were Qingpi（Pericarpium Citri Reticulatae Viride）

Zhiqiao（Fructus Aurantii）

Gualou（Fructus Trichosanthis）

Xiangfu（Rhizoma Cyperi）and Houpo（Cortex Magnoliae Officinalis）.The top 5frequently-used drug pairs were Dahuang（Radix et Rhizoma Rhei）-Zhiqiao

Longdancao（Gentianae Radix）-Qingpi

Chenxiang（Lignum Aquilariae Resinatum）-Qingpi

Danggui（Radix Angelicae Sinensis）-Xiangfu and Chishao（Radix Paeoniae Rubra）-Xiangfu.The top 5frequently-used three-drug combinations were Danggui-Zhiqiao-Xiangfu

Longdancao-Zhizi（Fructus Gardeniae）-Qingpi

Banxia（Rhizoma Pinelliae）-Qingpi-Gualou

Chenxiang-Yanhusuo（Rhizoma Corydalis）-Qingpi and Banxia-Gualou-Huanglian（Rhizoma Coptidis）.The top 5frequently-used formula compositions were qi-regulating medicinals+damp-transforming medicinals with aroma+heat-clearing phlegm-transforming medicinals

qi-regulating medicinals+damp-transforming medicinals with aroma+heat-clearing dampness-drying medicinals

qi-regulating medicinals+heat-clearing phlegm-transforming medicinals+heat-clearing dampness-drying medicinals

qi-regulating medicinals+damp-transforming medicinals with aroma+cold phlegm warming and transforming medicinals and qi-regulating medicinals+heat-clearing phlegm-transforming medicinals+ cold phlegm warming and transforming medicinals.Conclusion The commonly used medicinals for chest impediment in MRQC are qi-regulating medicinals combined with heat-clearing

phlegm-transforming or blood-quickening medicinals.

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