Objective To retrospectively analyze the effect of qi-boosting

yin-nourishing blood-quickening medicinal on the recurrence of patients with cryptogenic organizing pneumonia（COP）.Methods Thirty patients diagnosed with COP in the China-Japan Friendship Hospital from January 2006 to August 2012 were analyzed.Fourteen patients in the control group were given prednisone orally and 16 patients in the treatment group were added with qi-boosting

yin-nourishing blood-quickening medicinal.The treatment lasted for 6 to 12 months in both groups.The recurrence rate

recurrence time and adverse reactions were observed after treatment.Results There were 3 cases and 8 cases of recurrence in the treatment group and control group respectively.The recurrence rate in the treatment group was 18.75%

which was significantly lower than 57.14% in the control group（P<0.05）.The recurrence time in the treatment group was 4 to 8 months after using prednisone with an average of（10.72±0.73） months.The recurrence time in the control group was 3 to 10 months after using prednisone with an average of（7.91±1.04） months.The average recurrence time in the treatment group was significantly longer than that in the control group（P<0.05）.The adverse reaction rate in the control group and treatment group was 71.43% and 43.75% respectively

with no significant difference between groups（P>0.05）.Conclusion The combination of qi-boosting

yin-nourishing blood-quickening medicinal in hormone therapy for COP can obviously decrease the recurrence rate and prolong the recurrence time.