Objective To research the therapeutic effect of Shenling Fuzheng Capsule[right-supporting capsule of Dangshen（Radix Codonopsis）and Lingzhi（Ganoderma）]combined with highly active antiretroviral therapy（HAART）on 60cases of human immunodeficiency virus infection/acquired immunodeficiency syndrome（HIV/AIDS）.Methods Sixty cases of HIV/ AIDS were randomized to the treatment group and control group

with 30in each.The treatment group was given Shenling Fuzheng Capsule and HAART.The control group was given HAART.The treatment lasted for 6months.The therapeutic effect

common adverse reactions

quality of life（QOL）and renal function were observed in both groups.Results There were 30and 29effective cases in the treatment group and control group respectively

with no significant difference between groups（P>0.05）.The scores of physiology

emotion

independence

overall health status and QOL were significantly improved in the treatment group after treatment（P<0.05）.The scores of independence

overall health status and QOL were significantly improved in the control group after treatment（P<0.05）.The scores of physiology

emotion

overall health status and QOL in the treatment group were significantly higher than those in the control group（P<0.05）.After treatment

patients in the treatment group experienced nausea（or vomiting）

fatigue

dizziness

diarrhea

abdominal distension

abnormal liver function or bone marrow suppression.The patients in the control group experienced nausea（or vomiting）

fatigue

dizziness

rash

abnormal liver function or bone marrow suppression.There were significant differences between groups in nausea（or vomiting） and fatigue（P<0.05）

but with no significant difference between groups in other symptoms（P>0.05）.Conclusion Shenling Fuzheng Capsule combined with HAART can improve QOL and reduce the incidence of nausea（or vomiting）and fatigue in HIV/AIDS patients.