Effects of Jianpi Yiqi Huatan Formula on Left Ventricular Remodeling and Cardiac Function in Acute Myocardial Infarction Patients after Percutaneous Coronary Intervention
SUN Jianguang, GAO Junqing, XU Youlong, et al. Effects of Jianpi Yiqi Huatan Formula on Left Ventricular Remodeling and Cardiac Function in Acute Myocardial Infarction Patients after Percutaneous Coronary Intervention[J]. Journal of Traditional Chinese Medicine2013, 54(24): 2100-2102.
SUN Jianguang, GAO Junqing, XU Youlong, et al. Effects of Jianpi Yiqi Huatan Formula on Left Ventricular Remodeling and Cardiac Function in Acute Myocardial Infarction Patients after Percutaneous Coronary Intervention[J]. Journal of Traditional Chinese Medicine2013, 54(24): 2100-2102.DOI: 10.13288/j.11-2166/r.2013.24.026.
Objective To observe the therapeutic effect of Jianpi Yiqi Huatan Formula(formula to fortify the spleen
boost qi and transform phlegm) for acute myocardial infarction(AMI)patients after percutaneous coronary intervention(PCI).Methods One hundred AMI patients with spleen-deficiency phlegm turbidity-obstruction pattern after PCI were randomized into the treatment group and control group
with 50 in each.Both groups were given the conventional standardized treatment for one year.The treatment group was added with Jianpi Yiqi Huatan Formula for another 3 months after PCI.The therapeutic effect for angina pectoris was observed 6 months after PCI.The left ventricular diastolic diameter(LVDd)
ΔLVDd
left ventricular ejection fraction(LVEF) and ΔLVEF were observed before PCI and 3 months and 6 months after PCI.Results The total effective rate in the treatment group and control group was 96.00% and 90.00% respectively
with no significant difference between groups(P>0.05).Comparing with the pre-operation
LVEF and LVDd were significantly increased in both groups 3months and 6 months after PCI(P<0.05).There were significant differences between groups in LVEF and ΔLVEF 3 months and 6 months after PCI(P<0.05).The LVDd and ΔLVDd in the treatment group were significantly lower than those in the control group 6 months after PCI(P<0.05).Conclusion Jianpi Yiqi Huatan Formula can improve the cardiac function of AMI patients after PCI with an anti-left ventricular remodeling effect.