WANG Liqiong, LI Qing, SU Chunxiang, et al. Application and Evaluation of Blind Method in Randomize Controlled Trials of Chinese Medicine[J]. Journal of Traditional Chinese Medicine2014, 55(1): 28-33.
WANG Liqiong, LI Qing, SU Chunxiang, et al. Application and Evaluation of Blind Method in Randomize Controlled Trials of Chinese Medicine[J]. Journal of Traditional Chinese Medicine2014, 55(1): 28-33.DOI: 10.13288/j.11-2166/r.2014.01.008.
To analyze the current application of blind method and evaluate the design of ‘blinding’ in randomize controlled trials( RCTs) of Chinese medicine. Methods All RCTs on Chinese herbal medicine for irritable bowel syndrome( IBS) and acupuncture for insomnia in China National Knowledge Internet
VIP database
Chinese Biomedical Literature Database and Wanfang database were searched. Cochrane Handbook for Systematic Reviews of Interventions Version 5. 0. 2 was used. The literature was screened and the data was extracted by two researchers independently according to the inclusion criteria. The data was analyzed with SPSS17. 0. Results A total of 1 041 RCTs were included with 863 RCTs on Chinese herbal medicine for IBS and 177 RCTs on acupuncture for insomnia. The blind method was used in 32( 3. 1%) RCTs. There were 4( 16. 7%) RCTs reported the blinded objects and 3( 12. 5%) RCTs reported the detailed implementation program in 24( 2. 8%) RCTs on Chinese herbal medicine for IBS that used blind method. There were 2( 25%) RCTs reported the blinded objects and no RCTs reported the detailed implementation program in 8( 4. 5%) RCTs on acupuncture for insomnia that used blind method. Conclusion The research reflects that the application rate of blind method in TCM RCTs is very low
the report is incomplete and the quality of trial design is low.