Objective To observe the effect of electroacupuncture（ EA） in concha area on pain disorder and depression of streptozotocin（ STZ）-induced type 2 diabetes mellitus（ DM） rats. Methods Totally 36 Sprague Dawley（ SD） rats were randomized into the blank control group（ n = 10）

model group（ n = 13） and EA group（ n = 13）. The rats in the blank control group were fed with normal diet without any treatment. The rats in the model group and EA group were fed with high-fat diet and administrated with a single intraperitoneal injection of 50mg / kg STZ to establish type 2 DM models. Thirty days after modeling

the rats in EA group were given EA for 14 consecutive days. The body weight

blood glucose

behavioral score and delay time of claws pulled back because of thermal stimulation and mechanical stimulation were recorded before modeling and on the 3rd

15th and 30th day of modeling and 14th day of EA. Results Comparing with the blank control group

the body weights were significantly decreased

blood glucose values were significantly increased

behavioral scores were significantly decreased and delay time of claws pulled back because of thermal stimulation and mechanical stimulation were significantly prolonged in the model group and EA group after modeling（ P < 0. 05 or P < 0. 01）. Comparing with the model group

the body weights were significantly increased

blood glucose values were significantly decreased

behavioral scores were significantly increased and delay time of claws pulled back because of thermal stimulation and mechanical stimulation were significantly shortened in the EA group after EA（ P < 0. 05 or P < 0. 01）. Conclusion EA in concha area can relieve emaciation

hyperglycemia

depression and pain disorder in STZ-induced type 2 DM rats.