1. 桂阳县第一人民医院
2. 湖南中医药大学第一附属医院
纸质出版:2014
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[1]曾志成,彭清华.退翳明目汤对翼状胬肉切除术后基础泪液分泌和泪膜稳定性的影响[J].中医杂志,2014,55(03):218-221.
ZENG Zhicheng, PENG Qinghua. Effects of Tuiyi Mingmu Decoction on Basal Tear Secretion and Tear Film Stability After Pterygium Excision[J]. Journal of Traditional Chinese Medicine2014, 55(3): 218-221.
[1]曾志成,彭清华.退翳明目汤对翼状胬肉切除术后基础泪液分泌和泪膜稳定性的影响[J].中医杂志,2014,55(03):218-221. DOI: 10.13288/j.11-2166/r.2014.03.011.
ZENG Zhicheng, PENG Qinghua. Effects of Tuiyi Mingmu Decoction on Basal Tear Secretion and Tear Film Stability After Pterygium Excision[J]. Journal of Traditional Chinese Medicine2014, 55(3): 218-221. DOI: 10.13288/j.11-2166/r.2014.03.011.
目的观察退翳明目汤对翼状胬肉切除术后患者基础泪液分泌和泪膜稳定性的影响。方法将60例(84眼)翼状胬肉患者随机分为治疗组(30例
41眼)和对照组(30例
43眼)。治疗组在翼状胬肉切除术后予以退翳明目汤口服
对照组仅行翼状胬肉切除术
观察两组患者术前及术后2周、4周干眼症状计分、基础泪液分泌试验(Schirmer-Ⅰ)和泪膜破裂时间(BUT)
并随访观察两组患者12个月内胬肉复发情况。结果术后2周两组患者的干眼症状计分与术前比较有所提高
术后4周较术前明显降低(P<0.05或P<0.01)。治疗组术后2周、4周Schirmer-Ⅰ试验与术前比较明显提高(P<0.01)。两组术后2周、4周BUT与术前比较均明显提高(P<0.05或P<0.01)。两组术后2周、4周治疗组干眼症状计分、Schirmer-Ⅰ试验、BUT均优于对照组(P<0.05或P<0.01)。治疗组随访29例(40眼)
复发率为0
对照组随访28例(40眼)
复发率为15.00%
两组比较差异有统计学意义(P<0.05)。结论翼状胬肉切除术后配合口服退翳明目汤能够减轻患者干眼症状
促进泪液基础分泌量
改善泪膜稳定性
降低术后胬肉复发率。
Objective To observe the effects of Tuiyi Mingmu Decoction( screens-abating and eyes-brightening decoction) on basal tear secretion and tear film stability after pterygium excision and discuss its relationship with pterygium recurrence.Methods Sixty cases( 84 eyes) of pterygium were randomized into the treatment group and control group
with 30 cases( 41 eyes) and 30 cases( 43 eyes) in each.Both groups were given pterygium excision.The treatment group was given Tuiyi Mingmu Decoction after pterygium excision.The dry eye symptom scores
Schirmer-I test and tear film break-up time( BUT) were observed in the 2nd week and 4th week after pterygium excision in both groups.The recurrence rate of pterygium within 12 months was observed.Results The corneal wound was smooth and flat and the grafts without significant edema
cloudy
infection or rejection after pterygium excision in both groups.The dry eye symptom scores were significantly increased in both groups 2 weeks after pterygium excision( P <0.05 or P <0.01)
but significantly decreased 4 weeks after pterygium excision( P <0.05 or P <0.01).The results of Schirmer-I test were significantly increased in the treatment group 2 weeks and 4 weeks after pterygium excision( P < 0.01).There was no significant difference between before and after pterygium excision in Schirmer-I test in the control group( P > 0.05).The BUT was significantly increased in both groups 2 weeks and 4 weeks after pterygium excision( P < 0.05 or P < 0.01).The treatment group was superior to the control group in dry eye symptom scores
Schirmer-I test and BUT 2 weeks and 4 weeks after pterygium excision( P < 0.05 or P < 0.01).There were29 cases( 40 eyes) were followed up in the treatment group and 40 eyes recovered.There were 28 cases( 40 eyes)were followed up in the control group
and 34 eyes recovered and 6 eyes relapsed with a recurrence rate of 15.00%.There was a significant difference between groups in the recurrence rate( P < 0.05).Conclusion Tuiyi Mingmu Decoction can relieve dry eye symptoms
promote basal tear secretion
improve tear film stability and reduce recurrence rate after pterygium excision.
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