Objective To study the correlation of patterns

indicators

large vessel disease（ LVD） and small vessel disease（ SVD） in acute ischemic stroke. Methods Totally 207 cases of acute ischemic stroke were divided into the LVD group and SVD group

with 87 and 120 in each. The patterns

medical history

complications

routine blood test

ultrasound examination of intracranial vascular and scores of National Institutes of Health Stroke Scale（ NIHSS）

modified Rankin Scale（ MRS） and activities of daily living（ ADL） scale were compared in both groups. The related factors were analyzed with logistic regression. Results There were significant differences between groups in the score of phlegm pattern

incidence of yin deficiency yang hyperactivity pattern

atrial fibrillation

coronary heart disease（ CHD）

history of heart disease

arrhythmia

lymphocyte ratio（ LYM%）

high-density lipoprotein cholesterol（ HDL-C）

low-density lipoprotein cholesterol（ LDL-C）

high Transcranial Doppler（ TCD） blood flow velocity

NIHSS score and MRS score（ P < 0. 05）. CHD history

LDL

high TCD blood flow velocity and MRS score were related to LVD（ P < 0. 05）. LDL was related to SVD（ P < 0. 05）. Conclusion LVD and SVD of acute ischemic stroke show different patterns.