Tripterygium belongs to Celastraceae

with a variety of pharmacological activities of anti-inflammatory

immunomodulatory

anti-proliferation and pro-apoptosis. But Tripterygium preparations are easy to damage the reproductive system

liver

kidney and blood system. The toxicity of Tripterygium preparations limits the clinical application. The combinative law of detoxifying formulas for Tripterygium preparations such as yin-nourishing blood-supplementing formula for preventing the toxicity of Tripterygium preparations on female reproductive system and yang-warming essence-replenishing formula for preventing the toxicity of Tripterygium preparations on male reproductive system was discussed in this article according to the toxicity features of Tripterygium preparations.