Objective To observe the efficacy of Shengxue Pills（pills to promote the production of blood

生血丸）for chemotherapy-induced myelosuppression. Methods Totally 64cases of non-small cell lung cancer

colon cancer

stomach cancer and breast cancer were randomized into the treatment group and control group

with 32in each.Both groups were given conventional chemotherapy.The patients in the treatment group began to taken Shengxue Pills 7days before chemotherapy

while the patients in the control group were given Yixuesheng Capsules（益血生）.One treatment course lasted for 28days.The counts of white blood cell（WBC）

hemoglobin（HGB）and platelet（PLT）were detected before treatment and on the 7th

14th and 21st day of treatment in both groups.The levels of CD3+

CD4+

CD8+

CD4+/CD8+

natural killer（NK）cells

interleukin-2（IL-2）

IL-10and interferon-γ（INF-γ）were detected before and after treatment.The scores of symptoms and Karnofsky performance status（KPS）were observed. Results The count of WBC was significantly decreased in the control group on the 7th day of chemotherapy（P<0.05）.The counts of WBC were significantly increased in both groups on 21st day of chemotherapy（P<0.05）

especially in the treatment group（P<0.05）.The levels of CD3+

CD4+and CD4+/CD8+were significantly increased in the treatment group（P<0.05）.The levels of CD3+and NK cells were significantly increased in the control group（P<0.05）.Comparing with the control group

the levels of CD4+and CD4+/CD8+were significantly increased in the treatment group（P<0.05）.The levels of IL-2and INF-γwere significantly increased in both groups after treatment（P<0.05）.The symptom scores were significantly decreased in both groups after treatment（P<0.01）.The scores of KPS were significantly increased in both groups after treatment（P<0.05）.There was no significant difference between groups in the scores of symptoms and KPS after treatment（P>0.05）. Conclusion Shengxue Pills can protect bone marrow function

enhance immune function

relieve clinical symptoms and improve quality of life

with a better efficacy in increasing the levels of CD4+and CD4+/CD8+as compared with Yixuesheng Capsules.