1. 天津医科大学研究生院
2. 天津市南开医院
纸质出版:2014
移动端阅览
[1]杨小霞,郭庆捷,曹泽伟.清胰片治疗轻型急性胰腺炎38例临床观察[J].中医杂志,2014,55(13):1127-1129.
YANG Xiaoxia, GUO Qingjie, CAO Zewei. Clinical Observation on 38 Cases of Mild Acute Pancreatitis Treated With Qingyi Tablets(清胰片)[J]. Journal of Traditional Chinese Medicine2014, 55(13): 1127-1129.
[1]杨小霞,郭庆捷,曹泽伟.清胰片治疗轻型急性胰腺炎38例临床观察[J].中医杂志,2014,55(13):1127-1129. DOI: 10.13288/j.11-2166/r.2014.13.014.
YANG Xiaoxia, GUO Qingjie, CAO Zewei. Clinical Observation on 38 Cases of Mild Acute Pancreatitis Treated With Qingyi Tablets(清胰片)[J]. Journal of Traditional Chinese Medicine2014, 55(13): 1127-1129. DOI: 10.13288/j.11-2166/r.2014.13.014.
目的观察清胰片治疗轻型急性胰腺炎的临床疗效。方法选择轻型急性胰腺炎患者76例
随机分为观察组和对照组各38例
两组均予禁食、鼻胃管减压、止痛、改善微循环等常规措施
同时予醋酸奥曲肽注射液0.1mg+生理盐水500ml静脉滴注
每天3次
治疗2周。观察组同时予清胰片1.2g鼻饲
每天3次
治疗2周
结束禁食后以同等剂量口服。观察临床疗效
比较两组患者腹痛缓解、体温回复及禁食的时间。分别在治疗前、治疗第2、4、6天测定血清胰淀粉酶、C反应蛋白水平。再将2周内治愈的患者(观察组37例
对照组31例)随机分为观察1组19例、观察2组18例和对照1组16例、对照2组15例。观察1组和对照1组在此基础上口服清胰片3个月
每天3次
每次1.2g
观察2和对照2组不给予治疗
观察各组的复发情况。结果观察组治疗后患者腹痛缓解时间、体温回复时间、禁食时间均短于对照组(P<0.05)。两组治疗第2、4、6天血清胰淀粉酶及C反应蛋白与治疗前比较均明显降低(P<0.05或P<0.01)。观察组治疗第2、4、6天血清胰淀粉酶、C反应蛋白水平与对照组同时间比较亦显著降低(P<0.01)。观察组治愈率为97.33%
对照组为81.58%
观察组治愈率明显优于对照组(P<0.01)。观察1组复发率为5.26%
明显低于观察2组的27.78%(P<0.05)。对照1组复发率为6.25%
明显低于对照2组的26.67%(P<0.05)。结论清胰片可提高轻型急性胰腺炎的临床疗效
出院后3个月内继续服用清胰片可减少轻型急性胰腺炎恢复期的远期复发率。
Objective To observe the therapeutic effect of Qingyi Tablets(清胰片)in treating mild acute pancreatitis. Methods Totally 76cases of mild acute pancreatitis were randomized into the observation group and control group
with 38in each.Both groups were given routine treatment.The observation group was added with nasal feeding of 1.2g Qingyi Tablets(清胰片)three times daily for two weeks.The patients in the observation group were orally taken the same dose of Qingyi Tablets after fasting.The efficacy was observed after treatment.The time of abdominal pain relief
body temperature recovery and fasting was compared between groups.The levels of pancreatic amylase and C-reactive protein(CRP)were detected before and after treatment.Totally 37patients cured within 2weeks in the observation group were randomized into observation groupⅠof 19patients and observation groupⅡof 18cases.Totally 31patients cured within 2weeks in the control group were randomized into control groupⅠ of 16patients and control groupⅡ of 15cases.The patients in observation groupⅠand control groupⅠ were orally taken Qingyi Tablets(清胰片)for 3months.There was no treatment in observation groupⅡand control groupⅡ.The recurrence was observed in each group. Results The time of abdominal pain relief and fasting in the observation group was significantly shorter than that in the control group(P<0.05).The levels of pancreatic amylase and CRP were significantly decreased in both groups on the 2nd
4th
6th day of the treatment(P<0.05or P<0.01)
especially in the observation group(P<0.01).The cure rate in the observation group and control group was 97.33%and 81.58%respectively
with a significant difference between groups(P<0.05).The recurrence rate in observation group Ⅰ was 5.26%
significantly lower than that in observation group Ⅱ(27.78%
P<0.05).The recurrence rate in control groupⅠ was 6.25%
significantly lower than that in control groupⅡ(26.67%
P<0.05). Conclusion Qingyi Tablets(清胰片)can improve the efficacy of mild pancreatitis.Continued use of Qingyi Tablets(清胰片)within 3months after discharge can reduce the long-term recurrence rate of mild acute pancreatitis.
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