Objective To observe the efficacy of modified Xingshuian Formula（formula for carmful sleepy

醒睡安方） for narcolepsy. Methods Totally 46 cases of narcolepsy were given modified Xingshuian Formula one dose daily. The short-term efficacy was evaluated after 6-month treatment. The patients were followed up and the long-term efficacy was evaluated 6 months after withdrawal. The effective rates of symptoms such as daytime sleepiness

weight gain

cataplexy

sense of fear

appetite hyperactivity

sleep paralysis

dreaminess

hallucinations

irritability

sleep twitching and sleep talking were observed. Results The total short-term efficacy and long-term efficacy was 95. 7%and 80. 4% respectively. All the symptoms were reduced after treatment. The effective rates of daytime sleepiness

weight gain

cataplexy

sense of fear

appetite hyperactivity

sleep paralysis

dreaminess and hallucinations were higher than 60. 0%. Conclusion Modified Xingshuian Formula is effective for narcolepsy and it can obviously relieve the symptoms.