Objective To observe the efficacy of Huangdi Shenshuai Saoyang Lotion（ Lotion for uremic pruritus

黄地肾衰瘙痒洗液） for uremic pruritus of. Methods Seventy cases of uremic pruritus were randomized into the treatment group and control group

with 35 in each. Both groups were given basic treatment such as hemodialysis（2 or 3 times weekly and 4h once）. The patients in the control group were orally taken 10 mg Loratadine Tablets once daily. The patients in the treatment group were bathed with Huangdi Shenshuai Saoyang Lotion once daily. The treatment lasted for 15 days. The changes of itching points

serum creatinine（ Scr）

blood urea nitrogen（ BUN）

calcium（Ca） and phosphorus（P） were observed before and after treatment. The efficacy was evaluated. Results The total effective rate of the treatment group and control group was 91. 18% and 70. 59% respectively

with a significant difference between groups（ χ2= 4. 660

P = 0. 031）. The itching points were significantly decreased in both groups after treatment（P < 0. 01）

especially in the treatment group（P < 0. 05）. The levels of Scr

BUN and P were significantly decreased but the level of Ca was significantly increased in the treatment group after treatment（P <0. 05）. After treatment

the levels of Scr

BUN and P in the treatment group were significantly lower than those in the control group（P < 0. 05）. Conclusion Huangdi Shenshuai Saoyang Lotion can obviously relieve the symptoms of uremic pruritus and improve renal function

with a better efficacy as compared with Loratadine Tablets.