LIU Jianchun, YANG Wanfang, JI Xinyan, et al. On Brain-Targeting of Intranasal Administration With TCM Herbs[J]. Journal of Traditional Chinese Medicine2014, 55(15): 1284-1287.
LIU Jianchun, YANG Wanfang, JI Xinyan, et al. On Brain-Targeting of Intranasal Administration With TCM Herbs[J]. Journal of Traditional Chinese Medicine2014, 55(15): 1284-1287.DOI: 10.13288/j.11-2166/r.2014.15.007.
The anatomical structures and physiological functions of nasal cavity determine that nasal cavity is a direct and indirect passage of drug into the brain. The intranasal administration with TCM herbs has fast absorption and good efficacy with brain-targeting. The bioavailability of active ingredients in the brain can be enhanced with selection of dosage form