Objective To observe the effect of Huazhuo Jiedu Formula（ turbidity-transforming toxin-resolving formula） on patients with Hp-related chronic atrophic gastritis（ CAG）. Methods Sixty cases of CAG were randomized into the treatment group and control group

with 30 in each. The treatment group was given Huazhuo Jiedu Formula one dose daily. The control group was given triple bactericidal drugs（ 0. 5 g amoxicillin and 0. 5 g clarithromycin twice daily for 10 days） and 15 mg lansoprazole enteric-coated tablets once daily. The treatment lasted for 1month. The pathological form of gastric mucosa and Hp eradication rate were observed in both groups after treatment.Results The Hp eradication rate in the treatment group and control group was 85. 71% and 86. 21% respectively

with no significant difference between groups（ P > 0. 05）. There were significant differences between before and after treatment in the constituent ratios of no atrophy

moderate atrophy and severe atrophy in the treatment group（ P <0. 05）. There were significant differences between before and after treatment in the constituent ratios of mild atrophy and severe atrophy in the control group（ P < 0. 05）. There were significant differences between groups in the constituent ratios of no atrophy and severe atrophy after treatment（ P < 0. 05）. Conclusion The turbidity-transforming toxin-resolving therapy can effectively control Hp infection

with a same effect as compared with antibiotics and a better pathological effect as compared with triple bactericidal drugs.