GENG Jiawei, YU Qing. A Clinical Observation on Danggui Liuhuang Decoction for 32 Cases of Menopausal Insomnia[J]. Journal of Traditional Chinese Medicine2014, 55(18): 1581-1583.
GENG Jiawei, YU Qing. A Clinical Observation on Danggui Liuhuang Decoction for 32 Cases of Menopausal Insomnia[J]. Journal of Traditional Chinese Medicine2014, 55(18): 1581-1583.DOI: 10.13288/j.11-2166/r.2014.18.014.
Objective To observe the efficacy of Danggui Liuhuang Decoction( 当归六黄汤) for menopausal insomnia.Methods Totally 62 cases of menopausal insomnia were randomized into the treatment group of 32 cases and control group of 30 cases.The treatment group was given Danggui Liuhuang Decoction one dose daily.The patients in the control group were orally taken 1 mg of estazolam tablets( or 3 mg to 4 mg with severe symptoms) at bed time.The treatment lasted for 2 courses( 4 weeks).The efficacy was evaluated 2 weeks after withdrawal.The traditional Chinese medicine( TCM) syndrome scores were observed before and after treatment.The sleep time and wake time from 8 PM to 6 AM was recorded daily.Results The total effective rate of the treatment group and control group was 93.75% and 73.33% respectively
with a significant difference between groups( P < 0.05).The sleep time in the treatment group was significantly longer than that in the control group( P < 0.05).There was no significant difference between groups in the wake time( P > 0.05).The TCM syndrome scores were significantly decreased after treatment in both groups( P < 0.05).There were significant differences between groups in the scores of insomnia
dizziness
stretching
upset and chest tightness( P < 0.05).Conclusion Danggui Liuhuang Decoction is effective for menopausal insomnia.It can relieve TCM syndromes with no adverse reaction.