LU Chenghua, LU Junyan, GENG Peihua, et al. Clinical Observation on Compound Qinbu Pill for 35 Multi-drug Resistant Tuberculosis Patients with Qi-Yin Deficiency Syndrome[J]. Journal of Traditional Chinese Medicine2014, 55(21): 1826-1829.
LU Chenghua, LU Junyan, GENG Peihua, et al. Clinical Observation on Compound Qinbu Pill for 35 Multi-drug Resistant Tuberculosis Patients with Qi-Yin Deficiency Syndrome[J]. Journal of Traditional Chinese Medicine2014, 55(21): 1826-1829.DOI: 10.13288/j.11-2166/r.2014.21.008.
Objective To observe the clinical effect of Compound Qinbu Pill in treating multi-drug resistant tuberculosis( MDR-TB) patients with qi-yin deficiency syndrome. Methods Totally 72 cases of MDR-TB were randomized into the treatment group and control group
with 36 in each. The patients in the control group were taken Feitai Capsule orally
5 capsules each time and 3 times daily. The treatment group was given compound Qinbu Pill
one dose daily. The treatment lasted for 3 months. The clinical efficacy
TCM symptom score and adverse reactions were observed. Results The total effective rate of the treatment group and control group was 82. 86% and 25. 81%respectively
with a significant difference between groups( P < 0. 01). After treatment
the scores of cough
hectic fever
shortness of breath
night sweating
spontaneous sweating
expectoration
dry throat and emaciation and the total TCM symptom scores in both groups were significantly decreased( P < 0. 01). The total TCM symptom score and the scores of shortness of breath
night sweating
spontaneous sweating and expectoration in the treatment group were significantly lower than those in the control group after treatment( P < 0. 05 or P < 0. 01). The therapeutic effect of shortness of breath
night sweating
spontaneous sweating and expectoration in the treatment group was significantly better than that in the control group( P < 0. 05 or P < 0. 01). There was no adverse reaction in both groups.Conclusion Compound Qinbu pill has a remarkable TCM clinical effect on qi-yin deficiency type MDR-TB. It is more effective than Feitai Capsule in relieving shortness of breath