1. 中国中医科学院中医临床基础医学研究所
2. 首都医科大学附属北京友谊医院
3. 中国人民大学统计学院
4. 中国人民解放军海军总医院
纸质出版:2014
移动端阅览
[1]王海燕,杨薇,谢雁鸣,孙勇,庄严,王永炎.真实世界胃恶性肿瘤患者发病及中医证候特点[J].中医杂志,2014,55(24):2143-2147.
WANG Haiyan, YANG Wei, XIE Yanming, et al. Real World Study on the Incidence and TCM Syndrome Characteristics of Patients with Gastric Carcinoma[J]. Journal of Traditional Chinese Medicine2014, 55(24): 2143-2147.
[1]王海燕,杨薇,谢雁鸣,孙勇,庄严,王永炎.真实世界胃恶性肿瘤患者发病及中医证候特点[J].中医杂志,2014,55(24):2143-2147. DOI: 10.13288/j.11-2166/r.2014.24.019.
WANG Haiyan, YANG Wei, XIE Yanming, et al. Real World Study on the Incidence and TCM Syndrome Characteristics of Patients with Gastric Carcinoma[J]. Journal of Traditional Chinese Medicine2014, 55(24): 2143-2147. DOI: 10.13288/j.11-2166/r.2014.24.019.
目的探讨真实世界胃恶性肿瘤患者发病特点及中医证候分布情况。方法采集2008年1月至2010年12月全国20家三级甲等医院20 989例胃恶性肿瘤住院患者信息
对患者诊断及辨证信息进行规范化后
提取患者一般信息及中医证候信息进行频次统计
并绘制雷达图对患者发病情况、死亡时间与节气关系进行分析。结果 20989例胃恶性肿瘤患者中男性15144例(75.13%)
女性5012例(24.87%)
性别记录缺失者833例;年龄中位数为60岁
18
4
4岁1463例
45
5
9岁5464例
60
7
4岁5768例
75
8
9岁1 809例
年龄记录缺失者6 485例。有出院主证记录的338例患者中
虚证173例占42.90%
包括脾胃虚损、气阴两虚、气血双亏、胃热伤阴;实证145例占51.19%
包括瘀毒内阻、肝胃不和、痰湿凝滞;其他20例占5.91%。40岁及以下患者中虚证1例(11.11%)
实证8例(88.89%);41
6
0岁患者中虚证64例(61.54%)
实证40例(38.46%);60岁以上患者中虚证108例(52.68%)
实证97例(47.32%)。患者入院与死亡时间雷达分布图显示
秋冬季节胃恶性肿瘤入院患者例数多于春夏季节;夏季胃恶性肿瘤死亡例数多于冬季;十二时辰中巳时以及申时胃恶性肿瘤死亡患者明显增多。结论胃恶性肿瘤多见于中老年及男性患者
青年患者以实证为主、中老年患者以虚证为主
秋冬季节胃恶性肿瘤住院患者增加
夏季和脾经、膀胱经循行时辰死亡患者增加。
Objective To explore the characteristics of incidence and distribution of traditional Chinese medicine( TCM) syndromes in patients with gastric carcinoma in real world. Methods Information of 20989 in-patients with gastric carcinoma was collected from 20 Class A Tertiary General Hospitals national wide from January
2008 to December
2010. After standardization of the data on diagnosis and TCM differentiation
general information and TCM syndromes were extracted to do frequency statistics and to make radar charts to analyze the relationship between disease incidence
time of death and solar terms. Results In 20 989 patients with gastric carcinoma
there were 15 144 males( 75. 13%)
5 012 females( 24. 87%)
and 833 cases lack of gender records. The median age was 60.There were 1 463 patients aged 18 to 44
5 464 aged 45 to 59
5 768 patients aged 60 to 74
1 809 aged 75 to 89
and6 485 cases lack of age records. There were 338 cases recorded with main syndromes when discharged. 42. 90% of those syndromes were deficiency syndromes
including deficiency in spleen and stomach
deficiency of qi and yin
deficiency of qi and blood
stomach heat harming yin; 51. 19% were excess syndromes
including blood stasis and toxin stagnation
disharmony between liver and stomach
phlegm and dampness stagnation; and 5. 91% were other syndromes. Among patients aged or younger than 40
one was with deficiency syndrome( 11. 11%) and 8 with excess syndrome( 88. 89%); in patients aged from 41 to 60
64 were with deficiency syndrome( 61. 54%) and 40 with excess syndrome( 38. 46%); in patients over 60 years old
108 were with deficiency syndrome( 52. 68%) and 97 with excess syndrome( 47. 32%). The radar chart of patient admission time and death time showed that the number of admission in gastric cancer patients in autumn and winter were more than that in spring and summer. More deaths occurred in summer than in winter. In the 12 time periods of a day
deaths significantly increased during the periods from 9 am to 11 am and from 3 pm to 5 pm. Conclusion Patients with gastric carcinoma are mainly middle-aged and male. Young patients are mainly with excess syndromes
while elderly with deficiency syndromes. Hospitalization of patients with gastric carcinoma increases in autumn and winter. Deaths in patients increase in summer and when the spleen meridian or bladder meridian circulates.
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