Objective To investigate the related factors of endpoint events in myocardial infarction（ MI）patient. Methods Hospitalized cases with first diagnosis of acute myocardial infarction from January 2008 to December 2012 in Affiliated Hospital of Shandong University of Traditional Chinese Medicine were collected. In the period of hospitalization and follow-ups

cohort study questionnaire for the Chinese medicine hospital was applied to record general information

usage of traditional Chinese medicine（ TCM）

types and time of the endpoint events

number of occurrence and evidence. Logistic regression analysis was used to analyze the correlation of TCM intervention intensity

age

gender

complications

drug usage and other indicators with the occurrence of endpoint events.Results Totally 238 MI patients were included and 152 patients had complete follow-ups. In hospitalization

the top three endpoint events in MI patients were acute heart failure（ AHF

18. 49%）

cardiac death（ CD

16. 81%） and cardiogenic shock（ CGS

14. 45%）. In the follow-ups

the top three endpoint events were cardiac readmission（ 30. 19%）

CD（ 25. 16%） and AHF（ 13. 84%）. In hospitalization

TCM intervention intensity（ OR = 7. 753）and age（ OR = 1. 230） were related factors of CD

while age（ OR = 1. 055） was a related factor of AHF and age（ OR = 1. 072） was that of CGS. In the follow-ups

antithrombotic medication（ OR = 2. 831）

cholesterol-lowering medication（ OR = 2. 696）

pathoglycemia（ OR = 2. 734）

TCM intervention intensity（ OR = 1. 528） and age（ OR = 1. 053） were related factors of CD

while pathoglycemia（ OR = 2. 793）

TCM intervention intensity（ OR =1. 587） and age（ OR = 1. 054） were that of AHF and age（ OR = 1. 074） was that of severe arrhythmia. Conclusion TCM intervention

age

complications were related factors to the endpoint events in MI patients and TCM intervention could effectively prevent CD and AHF in follow-ups.