Objective To conclude SHEN Minhe’s laws of syndrome differentiation prescription in the treatment of brain tumor. Methods Records of 75 patients with brain tumor

who visited SHEN Minhe’s clinic from February2012 to February 2014

with 624 clinical visits in total

were collected. Clinical information was collected and clinical prescription database was established to conduct descriptive analysis on the cumulative frequency

categories

and natures and tastes of medicinals. Also cluster analysis was applied to 50 medicinals with the highest frequency.Results Totally 245 medicinals were prescribed in 624 clinical visits with 75 patients. The cumulative frequency of medicinals was 7017

in which Quanxie（ Scorpio

全蝎） had the highest frequency

followed by Fuling [Poria cocos（ Schw.） Wolf

茯苓]

Chuanxiong（ Ligusticum chuanxiong hort

川芎）

Chenpi（ Citrus reticulata Blanco

陈皮）

Gouqizi（ Lycium barbarum L.

枸杞子）

Honey cooked Gancao（ Radix Glycyrrhizae

炙甘草）

stir-fried Baizhu（ Atractylodes macrocephala

炒白术）

Yujin（ Curcuma petiolata

郁金）

proccessed Banxia（ Pinellia ternata

制半夏）. The most frequently used medicinal category was tonify deficiency medicine

followed by the categories of suppressing liver to stop liver-wind

activating blood to dissolve stasis

clearing the heat

and clearing damp and promoting diuresis. The most frequently used nature was neutral

while the most frequently appeared flavor was sweet.The medicines were classified into 29 categories by cluster analysis

involving formulas including Banxia Baizhu Tianma Tang

Qiju Dihuang Wan

Buyang Huanwu Tang

and medicinal pairs including Yujin（ Curcuma petiolata

郁金）and Shichangpu（ Acorus tatarinowii

石 菖 蒲）

Sharen（ Amomum villosum Lour.

砂 仁） and Doukou（ Alpinia katsumadai

草豆蔻）

Nüzhenzi（ Ligustrum lucidum Ait.

女贞子） and Mohanlian（ Herba Echiptae

墨旱莲）

Chuanxiong（ Ligusticum chuanxiong hort

川芎） and Gegen（ Puerariae Radix

葛根）

Zhishi（ Citrus aurantium L.

枳实） and Houpo（ Magnolia officinalis Rehd. et Wils.

厚朴）

Gouteng [Uncaria sinensis（ Oliv.） Havil.

钩藤]and Shijueming（ Concha Haliotidis

石决明）

Tianhuafen（ Trichosanthis Radix

天花粉） and Maidong（ Ophiopogon japonicus

麦冬）. Conclusion In the treatment of brain tumor

Dr. SHEN Minhe mainly invigorates the spleen and kidney with the supplemental methods and associates with methods of stopping liver-wind and unclogging meridians

activating blood to remove stasis

resolving toxins to resist cancer

and expelling phlegm and alleviating water retention. And he is good at prescribing Chinese medicines with nature of sweet

pungency

bitter and neutral as compatibility in clinic.