Objective To observe the clinical efficacy of Compound Longxuejie Capsules combined with western medical routine treatment on 40 patients with acute myocardial infarction（ AMI）. Methods Eighty AMI patients were randomly divided into observation group and control group

with 40 in each. For 30 days

on the basis of routine western medical treatment

the observation group was given Compound Longxuejie Capsules

1. 2 g each time

3 times per day

while the control group was given spironolactone instead

30 mg per time

1 time per day. Left ventricular end diastolic（ LVED）

serum levels of potassium

alanine aminotransferase（ ALT）

aspartate aminotransferase（ AST）

serum creatinine（ SCr）

blood urea nitrogen（ BUN）

creatine kinase（ CK）

creatine kinase isoenzyme（ CK-MB） and cardiac troponin（ TNT） were detected before and after treatments. Results The total clinical efficiency in the observation group was 100%

which was higher than that in the control group（ 80%

P < 0. 05）. There was no significant difference in serum levels of potassium in both groups between before and after treatment（ P >0. 05）. After treatment

LVED in the observation group was lower than that before treatment in the same group and after treatment in the control group（ P < 0. 05）. The levels of ALT

AST

SCr

BUN

CK

CK-MB

and TNT were significantly improved after treatments in both groups（ P < 0. 05）

but the levels of ALT

AST

SCr

CK

CK-MB and TNT in the observation group were lower than those in the control group（ P < 0. 05）

and the BUN level in the observation group was higher than that in the control group（ P < 0. 05）. Conclusion Applying western medical treatment combined with Compound Longxuejie Capsules on AMI patients could improve clinical efficacy notably and better patient’s biochemical indexes.