Objective To evaluate the clinical applicability of existing traditional Chinese medicine（ TCM） clinical practice guidelines. Method This study was performed with questionnaire survey. A protocol questionnaire designed by State Administration of Traditional Chinese Medicine was adopted to evaluate the clinical applicability of TCM clinical diagnosis and treatment guidelines. The clinical practice guidelines on 12 kinds of diseases promulgated in 2008 and 2012 were investigated

and analyzed with statistical method in respect to the general information

quality

application status and advice / suggestions. Result The application rate of guidelines

2012 edition was 91. 67%

which was higher than of the 2008 edition（ 31. 67%

P < 0. 05）. Quality level and clinical application rate of 2012 edition was higher than those of the 2008 edition（ P < 0. 05）. Doctors who have used the guidelines gave more positive assessment on the quality level and clinical application than those who have not yet used them（ P < 0. 05）. No statistical significant difference shows among doctors with different professional titles（ P > 0. 05）. Conclusion Clinical guidelines in 2012 edition are more accepted in clinicians. It is suggested that timely quality evaluation and applicability assessment is necessary. Regular updates and better promotion for the guidelines should be performed.