Objective To observe the effect of navel application of Zengye Tongbian Formula（ ZTF） combined with waxbag moxibustion（ WM） in the treatment of diabetic constipation with qi and yin deficiency. Methods Totally90 cases of diabetic constipation with qi and yin deficiency were randomly assigned to treatment group A（ navel application of ZTF）

treatment group B（ navel application of ZTF with WM） and control group（ Liuwei Anxiao Capsules）. The course of the treatment lasted for 2 weeks. The constipation symptom score

TCM symptom scores and quality of life（ QOL） were evaluated before treatment

two weeks after treatment and 3 months after the ending of treatment to determine the clinical efficacy. Results The constipation symptom scores and TCM symptom scores declined

while the quality of life improved significantly after treatment and during follow-ups in the treatment groups A and B（ P < 0. 01）. Compared with the control group

the constipation symptom scores and TCM symptom scores in the treatment groups A and B were significantly lower（ P < 0. 05）

and the QOL in group B was significantly higher（ P < 0. 05）. There was no significant difference in the total efficiency rates among the groups after treatments（ P >0. 05）. During follow-ups

the efficiency rates in group A and B were 71. 43% and 89. 66%

respectively

which were significantly higher than the 20. 00% in the control group and indicated that group B had better results（ P <0. 01）. Conclusion The clinical effect of navel application of ZTF was better than Liuwei Anxiao Capsules in the treatment of diabetic constipation with qi and yin deficiency. Moreover

the effect on QOL and long-term effect on constipation of navel application of ZTF with WM were superior to navel application alone.