Objective To observe the impact of periocular massage and acupoint application of Chinese medicine on the accommodative function of adolescent patients with nearwork-induced low myopia and asthenopia. Methods In total 82 adolescent patients with nearwork-induced low myopia and asthenopia were randomly divided into 2-week treatment group（ n = 28）

4-week treatment group（ n = 29） and control group（ n = 25）. Both treatment groups were conducted with periocular massage and acupoint application for 2 and 4 weeks respectively

while the control group was applied with the Esculin and Digitalis Glycosides Eye Drops for 4 weeks. The scores of asthenopia symptoms and accommodative function were assessed before treatments

2 weeks and 4 weeks after treatments. Results After the treatments

the scores of asthenopia symptoms in all groups were significantly improved（ P < 0. 01） but there was no significant difference among the results of each group（ P = 0. 615）

and the accommodative function

amplitude of accommodation

accommodative facility

accommodative lag

and negative relative adjustment（ NRA） / positive relative adjustment（ PRA） were significantly improved in each group（ P < 0. 01）. Moreover

the 4-week treatment group had the best results in the accommodative facility and accommodative lag（ P < 0. 05）. Conclusion Compared with the Esculin and Digitalis Glycosides Eye Drops

periocular massage and acupoint application of Chinese medicine could make more improvements on the accommodative facility

accommodative lag

and NRA.