Objective To observe the intervention effect of mid-summer patches on child repetitive respiratory infection based on the theory of treating winter disease in summer. Methods On the basis of epidemiological investigation of 8201 3-6 years old children from 44 kindergartens in Dongcheng District and Chaoyang District in Beijing

855 children with repetitive respiratory infection were selected to be study subjects. Enrolled children were randomly divided into intervention group（ n = 427） and control group（ n = 428）. Application with warming lung and reducing phlegm herbal medicine patches at Points Da Zhui（ DU14）

Danzhong（ RN17）

Feishu（ BL13）（ bilateral） and Gaohuang（ BL43）（ bilateral） was given to the intervention group

and application with placebo patches at the same acupoints was given to control group. Treatment course was from the first day of each dog-day

one application was given for 4 hours every three days

3 times each dog-day

for 3 dog-days in total. One treatment course was given each year for three consecutive years

and the intervention effect of mid-summer patches on child repetitive respiratory infection was observed and followed up for 3 years. Patients were followed up in every June and December for three years to observe the effective rate

onset frequency

and days of repetitive respiratory infection after point application treatment.Results According to intention to treat and per-protocol population set analysis

up to the second year of application

total effective rate was 52. 0% and 50. 5% respectively

in intervention group

and 44. 9% and 49. 3% respectively

in control group

with no significant difference between the two groups（P > 0. 05）. But in the third year

total effective rate was 70. 3% and 78. 1% respectively

in intervention group

and 61. 4% and 68. 0% respectively

in control group.The intervention group was obviously superior to the control group（ P < 0. 05）. Mid-summer patches had remarkable effects on decreasing onset frequency（ P < 0. 05）. Conclusion Mid-summer patches had definite therapeutic effect on preventing child repetitive respiratory infection. The suitable appropriate intervention course was 3 years.