Objective To observe clinical effects of low-frequency pulse stimulating acupuncture points treating diabetic peripheral neuropathy. Methods To observe the clinical effects of low-frequency pulse stimulation at acupuncture points on diabetic peripheral neuropathy. Methods 84 patients suffering from diabetic peripheral neuropathy were randomly divided into a treatment group of 42 cases and a control group of 42 cases. Both groups all received basic treatment like diet control

exercise

and medication to control blood glucose. Control group was added with Mecobalamin pills orally

0. 5 mg each time

three times per day; while treatment group was treated with lowfrequency pulse therapeutic apparatus to stimulate bilateral acupuncture points including Pishu（ BL20）

Shenshu（ BL23）

Zusanli（ ST36）

Sanyinjiao（ SP6）

and Yongquan（ KI1）

15 min each time

once per day. Both groups were treated for 2 weeks before clinical effects were evaluated. Clinical symptoms

physical signs and nerve conductive velocity were observed before and after the treatment. Results The total effective rate of clinical effects was76. 19% in treatment group

and 35. 71% in the control group. Treatment group was superior to the control group（ P < 0. 01）. After treatment

scores of clinical symptoms and physical signs remarkably decreased in both groups（ P < 0. 05 or P < 0. 01）

especially in treatment group（ P < 0. 01）. There were no statistically significant differences in conductive velocity of common peroneal nerve and tibial nerve between before and after treatment in control group（ P > 0. 05）. After treatment

conductive velocities of sensory nerves and motor nerves of common peroneal nerve and tibial nerve in treatment group increased remarkably

and those conductive velocities were remarkably superior to that in the control group（ P < 0. 01）. Conclusion Treatment with low-frequency pulse stimulation at acupuncture points can remarkably improve clinical symptoms

physical signs and nerve conductive velocity in patients suffering from diabetic peripheral neuropathy.