Acquired immune deficiency syndrome（ AIDS）

as an infectious disease

was lack of systematic theoretical researches of traditional Chinese medicine（ TCM） formerly. Therefore

TCM etiology and pathogenesis

syndrome principle and therapeutic method and prescription of AIDS are systematically discussed in this article."poison impairing vitality" and "deficient spleen Qi as the root"are proposed as its etiology and pathogenesis. Its TCM syndrome distributional principles were clearly described and the basic syndrome differentiation scale was protocoled. AIDS’ therapeutic principles of "restoring vitality and detoxifying"and "replenishing Qi to invigorate spleen"were determined. The relevant prescriptions such as Fuzheng Paidu Pian（扶正排毒片） and Yi Ai Kang（益艾康）were invented. Ultimately

AIDS basic theoretical system of TCM was preliminarily established. It might help establishing the theoretical foundation of TCM prevention and treatment of AIDS and providing scientific basis for improving AIDS TCM clinical diagnosis and treatment efficacy.