Objective To explore Traditional Chinese Medicine（ TCM） syndrome regularity in acute stage of ischemic stroke patients in Chengdu area. Methods Cross-sectional study was conducted on 1341 patients（ permanent residents in Chengdu area for more than 5 years） with acute stage of ischemic stroke in West China Hospital of Sichuan University from January

2012 to December

2013. The questionnaire was answered. Data contained patients’ general information and related information of syndrome diagnosis elements was collected. Patients’ TCM symptoms

signs and main syndromes

the related factors of typing syndromes by gender（ male or female）

hemiplegic limbs（ left or right）

age（ younger than 40

40 to 70 or more than 70）

and course of disease（ less than 72 h or more than 72 h） were analysed. Results 40 TCM symptoms could be divided into categories of wind

fire

phlegm

Qi deficiency

blood stasis and Yin deficiency. Qi deficiency syndrome contained the most symptoms and signs

while blood stasis syndrome contained the less. Among 1341 patients

there were 1073 cases with attack on meridians and 268 cases with attack on Zang-Fu organs. The order from the most frequency syndrome to the least frequency syndrome in the category of attack on meridians syndromes were wind-phlegm obstructing collateral

Yin deficiency and wind formation

phlegm-stasis obstructing collateral

Qi deficiency and blood stasis

and phlegm-heat and Fu-organ excess. The order from the most frequency to the least frequency syndrome in the category of attack on Zang-Fu organs syndromes were the upper orifices stagnation by phlegm and internal block due to phlegm-heat. There was no significant difference in TCM syndromes distribution in patients of different gender and age（ P > 0. 05）.Patients whoes course ≤ 72 h were mainly with wind-phlegm obstructing collateral syndrome

while those whoes course > 72 h were mainly with Yin deficiency and wind formation syndrome. Patients with right hemiplegic limbs were mainly with the upper orifices stagnation by phlegm

phlegm-stasis obstructing collateral and internal block due to phlegm-heat syndromes. Patients with left hemiplegic limbs were mainly with wind-phlegm obstructing collateral

Yin deficiency and wind formation syndromes. Conclusion Patients with acute stage of ischemic stroke in Chengdu area are mainly with wind-phlegm obstructing collateral

the upper orifices stagnation by phlegm

Yin deficiency and wind formation syndromes. The length of course and hemiplegic side may influence TCM syndromes diagnosis.