YUAN Dan. Analysis on Medication Regularity of WANG Shouchuan in the Treatment of Pediatric Epilepsy[J]. Journal of Traditional Chinese Medicine2015, 56(14): 1205-1207.
YUAN Dan. Analysis on Medication Regularity of WANG Shouchuan in the Treatment of Pediatric Epilepsy[J]. Journal of Traditional Chinese Medicine2015, 56(14): 1205-1207.DOI: 10.13288/j.11-2166/r.2015.14.011.
Objective To summarize the medication compatibility regularity by Professor WANG Shouchuan in the treatment of pediatric epilepsy using data mining technology. Methods Seventy-five cases of epileptic children who had seen doctor WANG Shou-chuan from August 2012 to August 2013 were selected to extract the prescription information to form database of Chinese herbs prescription. The frequency of drug usage and correlation frequentness among single Chinese herb were analyzed
and visual processing was made with complex network analysis to the above-mentioned high correlation frequentness compatibility of Chinese herbs. Results Seventy-five cases were treated for 140 times at all and 94 kinds of Chinese herbs were used for a total of 2023 times. There were a total of 21 kinds of Chinese herbs that were used not less than 25 times. and the top five in proper order were Gouteng( Uncaria
钩藤)( 123)
Shi Changpu( Acorus gramineus
石菖蒲)( 114)
Tianma( Gastrodia elata
天麻)( 113)
Yujin( Radix curcumae
郁金)( 112)
and Yuanzhi( Polygala tenuifolia
远志)( 100). Taked correlation frequentness equal to or no less than 151 as the intercept point
28 groups of the relevant medicine pairs were involved
and the top three of most frequent used pairs were Tianma and Gouteng( 110)
Yujin and Touteng( 99)
and Yujin and Shi Changpu( 98). Complex network analysis showed that Gouteng
Shi Changpu
Tianma
Yujin
Yunazhi were core drugs
which often combined with Fuling( Poria cocos
茯苓)
Zhi Jiangcan( Bombyx batryticatus
制僵蚕)
Jili( Caltrop
蒺藜)
and Dannanxing( Bile arisaema
胆南星). Conclusion With stopping the wind
removing phlegm to induce resuscitation as basic rules
Professor WANG Shou-chuan often combined with methods of tonifying spleen and kidney and calming and nourishing liver in the treatment of pediatric epilepsy. The core drugs in his prescriptions were Gouteng