With the development of systems biology

traditional Chinese medicine（ TCM） ecological system makes collision and amalgamation to systems analysis methods

such as network pharmacology

metabolomics

proteomics

genomics and so on

producing a TCM syndrome differentiation of "causal status and target". System biology provides great convenience to reveal the essence of the TCM "status"and the mechanism of " adjust state". TCM can take example by abundant syndrome differentiation theory of modern medical technologies such as anatomy

physiology

pathology and pharmacology to make a deeper amalgamation between Chinese and western medicine from technology to theory. Based on traditional thinking of syndrome differentiation

TCM clinical advocates medication suit the symptoms

medication suit the diseases and medication according to cause to improve target for treating. Based on clinical practice

the authors put forward "cross"prescription strategy of "causal status and target"

that is to say

reference according to the disease

based on status

syndrome（ indicators） as the target

cause as the first

according to result and paying omnibearing attention to medication strategy of disease in order to improve the clinical curative effect.