Objective To explore the clinical curative effect of adjuvant therapy of Danhong Injection combined with Shenmai Injection in the treatment of chronic heart failure with Qi and yin deficiency. Methods Ninety patients with chronic heart failure with Qi and yin deficiency were randomly divided into a treatment group and a control group

with 45 cases in each group. The control group was treated with 60 ml of Shenmai Injection in 200 ml of normal saline by intravenous drip

once daily

combined with conventional western medicine treatment; On the basis of the treatment for the control group

the treatment group was added with 20 ml of Danhong Injection in 250 ml of 5%glucose injection by intravenous drip once daily. The course of treatment was 2 weeks for both groups. The following index of patients in two groups were compared: the New York Heart Association（ NYHA） Functional Classification

the total score of heart failure and TCM syndrome

six minutes walking distance

serum level of amino terminal brain natriuretic peptide（ NT-pro BNP）

and ultrasonic echocardiography index. Results The total effective rate of NYHA function classification was 97. 78% in the treatment group

and 91. 11% in the control group

with no statistically significant difference between the two groups（ P>0. 05）. After treatment in both groups

the total score of heart failure and TCM Syndrome were significantly lower than those before treatment

left ventricular ejection fraction（ LVEF）

stroke volume（ SV）

and cardiac output（ CO） were improved

and six minutes walking distance increased（ P<0. 05）. After treatment

the total score of heart failure and TCM Syndrome in treatment group was lower than that in control group

and the six minute walk distance

as well as levels of LVEF

SV and CO were higher than those in control group（ P<0. 05）. After treatment and during the 2 months of follow-up

the serum level of NT-pro BNP in both groups were significantly decreased compared with that before treatment（ P<0. 05）. After treatment and during the 2 months of follow-up

the serum level of NT-pro BNP in the treatment group was significantly lower than that in the control group（ P<0. 05）. Conclusion Adjuvant therapy of Danhong Injection combined with Shenmai Injection can significantly improve the clinical symptoms of the chronic heart failure patients with Qi Yin deficiency type

increase the six minutes walking distance

reduce the levels of NT-pro BNP and improve heart function.