1. 深圳市光明新区人民医院
2. 广东省中医院
纸质出版:2016
移动端阅览
[1]肖莹莹,周仙仕,唐光华.脓毒症患者中医证候与预后的关系[J].中医杂志,2016,57(03):224-227.
XIAO Yingying, ZHOU Xianshi, TANG Guanghua. Relationship Between Chinese Medicine Syndrome and Prognosis of Sepsis Patients[J]. Journal of Traditional Chinese Medicine2016, 57(3): 224-227.
[1]肖莹莹,周仙仕,唐光华.脓毒症患者中医证候与预后的关系[J].中医杂志,2016,57(03):224-227. DOI: 10.13288/j.11-2166/r.2016.03.012.
XIAO Yingying, ZHOU Xianshi, TANG Guanghua. Relationship Between Chinese Medicine Syndrome and Prognosis of Sepsis Patients[J]. Journal of Traditional Chinese Medicine2016, 57(3): 224-227. DOI: 10.13288/j.11-2166/r.2016.03.012.
目的分析脓毒症患者的中医证候及证候要素
探讨其与脓毒症预后的关系。方法收集脓毒症患者51例
观察患者脓毒症类型
监测乳酸水平及症状、体征的变化
于纳入时、第2
3
天、第4
7
天进行中医辨证及证候要素分析及APACHEⅡ和MODS评分
计算28天病死率
并分析其影响因素。结果51例脓毒症患者中单纯脓毒症患者17例
脓毒症合并多器官功能障碍综合征(MODS)者34例。脓毒症合并MODS患者28天死亡率为47.06%(16/34)
单纯脓毒症患者无死亡病例(P
<
0.01)
纳入至第7天的死亡患者均为虚实夹杂证。患者纳入时、第2
3
天、第4
7
天均以虚实夹杂证最多(分别为40例、47例、42例)、实证次之(分别为11例、4例、9例)
无纯虚证。纳入时及第4
7
天时虚实夹杂证患者的APACHEⅡ评分和MODS评分均显著高于实证患者(P
<
0.05或P
<
0.01)。纳入时、第2
3
天、第4
7
天中
单纯脓毒症患者毒热证、气虚证呈下降趋势
痰证、瘀血证、阴虚证呈上升趋势
各时间点均未出现阳虚证;脓毒症合并MODS患者阴虚证均呈下降趋势
阳虚证呈上升趋势。结论脓毒症患者以虚实夹杂证为多
虚实夹杂证患者病情较纯实证患者更重
死亡率更高。
Objective To analyze the Chinese medicine syndromes and syndrome elements of sepsis patients and to discuss the relationship between syndromes and prognosis.Methods Fifty-one sepsis patients were collected
and their sepsis types were observed.Patients’ lactate level and changes of symptoms and signs were detected.Chinese medicine syndrome differentiation
syndrome elements analysis
Acute Physiology And Chronic Health EvaluationⅡ(APACHE Ⅱ)and multiple organ dysfunction syndrome(MODS)score were made when the cases were enrolled
on the 2nd to 3rd day and on the 4th to 7th day.The 28-day mortality rate was calculated
and the influencing factors were analyzed.Results There were 17 patients of single sepsis and 34 sepsis patients were with MODS.The 28-day mortality rate of patients with sepsis and MODS was 47.06%(16 /34).No death case in single sepsis patients(P < 0.01).Dead case till the 7th day were all of intermingled deficiency and excess syndrome.Intermingled deficiency and excess syndrome was the most when the cases were enrolled
on the 2nd to 3rd day and on the4 th to 7th day(40
47
42 cases respectively)
excess syndrome second(11
4
9 cases respectively)
no single deficiency syndrome.The scores of APACHEⅡ and MODS of intermingled deficiency and excess syndrome patients when the cases were enrolled and on the 4th to 7th day were much higher than those of excess syndrome patients(P <0.05 or P < 0.01).Toxic heat syndrome and Qi deficiency syndrome of single sepsis patients showed the downtrend when the cases were enrolled
on the 2nd to 3rd day and on the 4th to 7th day;while phlegm syndrome
blood stasis syndrome and Yin deficiency syndrome showed the uptrend
no Yang deficiency syndrome shown at these time points.Yin deficiency syndrome of patients with sepsis and MODS showed the downtrend;while Yang deficiency syndrome showed the uptrend.Conclusion Sepsis patients were mostly of intermingled deficiency and excess syndrome.Patients of this syndrome were more critical than of single excess syndrome
and the mortality rate was higher.
0
浏览量
427
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构
京公网安备11010102007558号