Objective To observe clinical curative effects and safety of Jiannao Yifang in the treatment of vascular dementia. Methods Sixty patients with vascular dementia with Qi deficiency to phlegm and stasis were collected and randomly divided into the treatment group and the control group

with 30 cases in each group. Two groups were given basic treatment（ nimodipine

20 mg each time

3 times a day）

and the treatment group also took Jiannao Yifang

1 dose a day. Both groups were treated for 6 weeks. Before and after treatment

score of mini-mental state examination scale（ MMSE）

score of ability of daily living scale（ ADL）

score of neuropsychiatric questionnaire（ NPI）

and the change of Chinese medical syndrome integral of patients in the two groups were recorded. The cognitive function

disposing capacity

spiritual behavior

and curative effects of Chinese medical syndrome were also evaluated. Results In clinical curative effects of cognitive function

effective cases accounted for 80. 00% of all cases in the treatment group

and 53. 33% in the control group. The treatment group was better than the control group（ P < 0. 05）. In clinical curative effects of disposing capacity

effective cases accounted for 23. 33% of all cases in the treatment group

and 30. 00% in the control group. There was no significant difference between the two groups（ P > 0. 05）. In clinical curative effects of spiritual behavior

effective cases accounted for 6. 67% of all cases in the treatment group

and 6. 67% in the control group. There was no significant difference between the two groups（ P >0. 05）. In curative effects of Chinese medical syndrome

effective cases accounted for 56. 67% of all cases in the treatment group

and 10. 00% in the control group. The treatment group was better than the control group（ P <0. 01）. MMSE scores of both groups after treatment were higher

but ADL scores decreased than those before treatment（ P < 0. 01）. Chinese medical syndrome integral of the treatment group after treatment was lower than that before treatment（ P < 0. 01）. There was statistically significant difference in Chinese medical syndrome integral between two groups after treatment（ P < 0. 01）. Conclusion The treatment of vascular dementia with Jiannao Yifang may improve cognitive function

ability of daily living and clinical symptoms of Chinese medicine of patients

with less adverse reaction.