Clinical Observation on Decoction of Clearing Heat,Promoting Dieresis,Invigorating the Circulation of Blood and Removing Toxin Combined with Western Medicine in Treating 75 Patients with Abdominal Type Anaphylactoid Purpura with Syndrome of Damp Toxin Accu
YANG Yan, CHENG Yan, ZHANG Keqing, et al. Clinical Observation on Decoction of Clearing Heat,Promoting Dieresis,Invigorating the Circulation of Blood and Removing Toxin Combined with Western Medicine in Treating 75 Patients with Abdominal Type Anaphylactoid Purpura with Syndrome of Damp Toxin Accu[J]. Journal of Traditional Chinese Medicine2016, 57(9): 763-766.
YANG Yan, CHENG Yan, ZHANG Keqing, et al. Clinical Observation on Decoction of Clearing Heat,Promoting Dieresis,Invigorating the Circulation of Blood and Removing Toxin Combined with Western Medicine in Treating 75 Patients with Abdominal Type Anaphylactoid Purpura with Syndrome of Damp Toxin Accu[J]. Journal of Traditional Chinese Medicine2016, 57(9): 763-766.DOI: 10.13288/j.11-2166/r.2016.09.012.
Objective To observe therapeutic effects of decoction of clearing heat
promoting dieresis
invigorating the circulation of blood and removing toxin combined with western medicine on abdominal type anaphylactoid purpura with syndrome of damp toxin accumulating inside. Methods A total of 111 children with abdominal type anaphylactoid purpura of damp toxin accumulating syndrome were randomly divided into treatment group( 75 cases)and control group( 36 cases). The control group was given intravenous drip with prednisolone sodium succinate
2 mg /( kg·d)
once every 12 h
and reduced the methylprednisolone according to state of illness after full dose for 3
5 days. At the same time the control group was given intravenous drip with vitamin C 0. 2 g and aminomethylbenzoic acid
50 mg once a day. Additionally
the treatment group orally took decoction of clearing heat
promoting dieresis
invigorating the circulation of blood and removing toxin
1 dose daily. Courses of treatment were 2 weeks. Before and after the treatment
respectively graded symptoms of abdominal pain
hemafecia
hematemesis
emesis
loss of appetite
abdominal distension
skin purpura and abdominal B ultrasonic and observed the time of abdominal pain disappearing in the two groups to evaluate clinical effects. Results In the treatment group
remarkably effective rate was85. 4%
total effective rate was 96. 0%
while that was 69. 5% and 94. 5% respectively in the control group. The difference between both groups was statistically significant( P
<
0. 05). After treatment
scores of abdominal pain
loss of appetite
abdominal distension
skin purpura and abdominal B ultrasonic and aggregate score of both groups were lower than those before treatment( P
<
0. 05). After treatment
scores of abdominal pain
loss of appetite and abdominal B ultrasonic and aggregate score in the treatment group were lower than those in the control group( P
<
0. 05). After treatment
hemafecia
hematemesis
emesis disappeared in the two groups. In the treatment group
the time of abdominal pain disappearing was shorter than that in the control group( P
<
0. 05). Conclusion The efficacy of clearing heat
promoting dieresis
invigorating the circulation of blood and removing toxin combined with western medicine for abdominal type anaphylactoid purpura with syndrome of damp toxin accumulating inside was superior to the treatment of only western medicine. It may obviously improve symptoms and signs and shorten the time of abdominal pain disappearing.